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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Objective: A method of early diagnosis of acute myocardial infarction (AMI) using high-sensitivity cardiac troponin-T (hs- TnT) has been introduced. This study was conducted to evaluate the accuracy of hs-TnT in patients with suspected AMI. Methods: Patients who were more than 20 years old with symptoms of AMI and who underwent hs-TnT and coronary angiography or echocardiography were included. Risk factors associated with AMI and basic characteristics were collected. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were evaluated. The effects of time from symptom onset to emergency department (ED) visit on test accuracy were analyzed. Results: The final analysis included 102 patients, of which 37 were AMI. The sensitivity and specificity of the hs-TnT was 59.5% (95% confidence interval [CI], 42.1% to 75.2%) and 67.7% (95% CI, 54.9% to 78.8%), respectively. In patients with typical chest pain, the sensitivity and specificity of the hs-TnT was 58.1% (95% CI, 39.1% to 75.5%) and 73.2% (95% CI, 57.1% to 85.8%), respectively. The NPV and sensitivity increased, and the PPV and specificity decreased as time from symptom onset to ED visit increased. Conclusion: The accuracy of the hs-TnT test was not as good in patients who visited the ED for symptoms suggestive of AMI. Therefore, to rule-in or rule-out AMI by using hs-TnT in ED, it is necessary to consider the electrocardiogram and clinical features, or to check variations by repeated measurement of hs-TnT.
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참고문헌 (13)
참고문헌 신청
Mueller C / 2016 / Multicenter evaluation of a 0-hour/1-hour algorithm in the diagnosis of myocardial infarction with high-sensitivity cardiac troponin T / Ann Emerg Med 68:76~87
Thygesen K / 2012 / Third universal definition of myocardial infarction / Circulation 126:2020~2035
Kook HY / 2014 / Current trend of acute myocardial infarction in Korea: from the Korea Acute Myocardial Infarction Registry from 2006 to 2013 / Am J Cardiol 114:1817~1822
Roger VL / 2010 / Trends in incidence, severity, and outcome of hospitalized myocardial infarction / Circulation 121:863~869
Fred S. Apple / 2014 / 고감도 심장성 Troponin 검사법의 분석특성 / Laboratory Medicine Online 4(1):55~62
Thygesen K / 2012 / Third universal definition of myocardial infarction / Circulation 126:2020~2035
Kook HY / 2014 / Current trend of acute myocardial infarction in Korea: from the Korea Acute Myocardial Infarction Registry from 2006 to 2013 / Am J Cardiol 114:1817~1822
Roger VL / 2010 / Trends in incidence, severity, and outcome of hospitalized myocardial infarction / Circulation 121:863~869
Fred S. Apple / 2014 / 고감도 심장성 Troponin 검사법의 분석특성 / Laboratory Medicine Online 4(1):55~62
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