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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 26 - 30 (5page)
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Purpose: The aim of this study is to identify risk factors of postthrombotic syndrome (PTS) and evaluate the efficacy of catheter-directed thrombolysis (CDT) for preventing the development of PTS in patients with lower extremity deep vein thrombosis (DVT). Materials and Methods: From 2005 January to 2013 December, 139 limbs of 126 patients were included in this study who had the first episode of proximal DVT at the affected limb and who had visited our out-patient clinic. CDT was performed on 55 limbs (39.6%). We achieved complete recanalization in 39 limbs (70.9%) and partial recanalization (residual thrombus <50.0%) in 16 limbs (29.1%). We retrospectively reviewed medical records for possible predictors of PTS. Results: Median follow-up duration was 83 months (range, 30-136 months). No differences were found between the CDT and non-CDT group in age, gender, duration of symptom, use of anticoagulation and recurrence of DVT. A significantly higher thrombotic burden was observed in the CDT group (P=0.009). In a binary logistic regression model, patients with PTS had significantly higher body mass index (BMI) (odds ratio [OR], 1.303; 95% confidence interval [CI], 1.079-1.574; P=0.006) and longer thrombotic burden involved in ilio-femoro-popliteal DVT (OR, 3.666; 95% CI, 1.093-12.296; P=0.035). CDT did not influence the risk of PTS (P>0.05). Conclusion: We suggest that CDT is not effective in preventing PTS, while higher BMI and longer thrombotic burden are associated with the development of PTS in patients with DVT.
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참고문헌 (26)
참고문헌 신청
Prandoni P / 2009 / Post-thrombotic syndrome: prevalence, prognostication and need for progress / Br J Haematol 145:286~295
Kahn SR / 2008 / Determinants and time course of the postthrombotic syndrome after acute deep venous thrombosis / Ann Intern Med 149:698~707
Prandoni P / 1996 / The long-term clinical course of acute deep venous thrombosis / Ann Intern Med 125:1~7
Kahn SR / 2002 / Effect of postthrombotic syndrome on healthrelated quality of life after deep venous thrombosis / Arch Intern Med 162:1144~1148
Kahn SR / 2006 / The post-thrombotic syndrome: progress and pitfalls / Br J Haematol 134:357~365
Kahn SR / 2008 / Determinants and time course of the postthrombotic syndrome after acute deep venous thrombosis / Ann Intern Med 149:698~707
Prandoni P / 1996 / The long-term clinical course of acute deep venous thrombosis / Ann Intern Med 125:1~7
Kahn SR / 2002 / Effect of postthrombotic syndrome on healthrelated quality of life after deep venous thrombosis / Arch Intern Med 162:1144~1148
Kahn SR / 2006 / The post-thrombotic syndrome: progress and pitfalls / Br J Haematol 134:357~365
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