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논문 기본 정보

자료유형
학술저널
저자정보
Ha Yeon Kim (Department of Internal Medicine Chonnam National University Medical School Gwangju) Department of radiology Chonnam National University Medical School G (Department of radiology Chonnam National University Medical School Gwangju) Byung Ki Kim (Department of Internal Medicine Saint Carollo Hospital Suncheon Jeollanam-do Korea) Minah Kim (Department of Internal Medicine Chonnam National University Medical School Gwangju) Eun Hui Bae (Department of Internal Medicine Chonnam National University Medical School Gwangju) Seong Kwon Ma (Department of Internal Medicine Chonnam National University Medical School Gwangju) Soo Wan Kim (Department of Internal Medicine Chonnam National University Medical School Gwangju)
저널정보
전해질고혈압연구회 Electrolytes & Blood Pressure Electrolytes & Blood Pressure Vol.16 No.2
발행연도
2018.1
수록면
23 - 26 (4page)

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A 22-year-old male patient was diagnosed with autosomal dominant polycystic kidney disease(ADPKD). He received conservative treatment with an angiotensin-converting enzyme inhibitor. Two years later, oral therapy, consisting of 60 mg tolvaptan per day, was initiated. Compared with height-adjusted total kidney volume, the rate of kidney growth reduced significantly from 7.33% to 0.66% annually, since commencement of the tolvaptan therapy. The liver enzyme profile and serum sodium level and osmolality were constantly within normal ranges. In Korea, this is the first reported case of a patient with ADPKD who received tolvaptan treatment for more than 1 year. This case demonstrates that long-term tolvaptan treatment appears to be safe, well tolerated, and effective for ADPKD.

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