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자료유형
학술저널
저자정보
Ji Min Choi (Department of Internal Medicine and Healthcare Research Institute) Jong In Yang (Department of Internal Medicine and Healthcare Research Institute) Seung Joo Kang (Seoul National University Hospital Healthcare System Gangnam Center) 한유민 (서울대학교병원) Jooyoung Lee (Department of Internal Medicine and Healthcare Research Institute) Changhyun Lee (Department of Internal Medicine and Healthcare Research Institute) Su Jin Chung (Department of Internal Medicine and Healthcare Research Institute) Dae Hyun Yoon (Department of Psychiatry Healthcare System Gangnam Center) Boram Park (Department of Internal Medicine and Healthcare Research Institute) Yong Sung Kim (Department of Gastroenterology and Digestive Disease Research Institute Wonkwang University School)
저널정보
대한소화관운동학회(현 대한소화기능성질환.운동학회) Journal of Neurogastroenterology and Motility (JNM) Journal of Neurogastroenterology and Motility (JNM) Vol.24 No.4
발행연도
2018.1
수록면
593 - 602 (10page)

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Background/Aims The different clinical manifestations of gastroesophageal reflux disease (GERD) may be influenced by associated psychological factors. We evaluated the psychological status (anxiety and depression) according to each subtype of GERD. Methods Subjects who underwent esophagogastroduodenoscopy and completed a symptom questionnaire between January 2008 and December 2011 were analyzed. The subjects were classified into the following groups: erosive reflux disease (ERD), non-erosive reflux disease (NERD), asymptomatic erosive esophagitis (AEE), and controls. Anxiety and depression were assessed using the State-Trait Anxiety Inventory and Beck Depression Inventory, respectively. Results We analyzed 19 099 subjects: 16 157 (84.6%), 176 (0.9%), 1398 (7.3%), and 1368 (7.2%) in the control, ERD, NERD, and AEE groups, respectively. Multiple multinomial logistic regression revealed a significant association of increased state (adjusted OR, 1.89; 95% CI, 1.53–2.33) and trait anxiety (adjusted OR, 1.78; 95% CI, 1.34–2.35) and depression (adjusted OR, 2.21; 95% CI, 1.75–2.80) with NERD. ERD group showed a significant association only with state anxiety (adjusted OR, 2.20; 95% CI, 1.27–3.81) and depression (adjusted OR, 2.23; 95% CI, 1.18–4.22). The AEE group, however, did not show any significant association with psychological factors. Conclusion This cross-sectional study revealed that anxiety and depression levels were significantly higher in subjects with GERD (notably in the NERD) than in controls.

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