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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 1 - 14 (14page)
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Clear cell carcinoma (CCC) of the ovary is known to show poorer sensitivity to chemotherapeuticagents and to be associated with a worse prognosis than the more common serousadenocarcinoma or endometrioid adenocarcinoma. To improve the survival of patients withovarian CCC, the deeper understanding of the mechanism of CCC carcinogenesis as well asthe efforts to develop novel treatment strategies in the setting of both front-line treatmentand salvage treatment for recurrent disease are needed. In this presentation, we firstsummarize the mechanism responsible for carcinogenesis. Then, we highlight the promisingtherapeutic targets in ovarian CCC and provide information on the novel agents which inhibitthese molecular targets. Moreover, we discuss on the cytotoxic anti-cancer agents that can bebest combined with targeted agents in the treatment of ovarian CCC.
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참고문헌 (71)
참고문헌 신청
Serov SF / 1973 / Histologic typing of ovarian tumors / World Health Organization
Anglesio MS / 2011 / Clear cell carcinoma of the ovary: a report from the first Ovarian Clear Cell Symposium, June 24th, 2010 / Gynecol Oncol 121:407~415
Oncology Committee of Japan Society of Obstetrics / 2010 / Annual report of the patients with ovarian cancers / Acta Obstet Gynaecol Jpn 62:827~910
Winter WE 3rd / 2007 / Prognostic factors for stage III epithelial ovarian cancer: a Gynecologic Oncology Group Study / J Clin Oncol 25:3621~3627
Sugiyama T / 2000 / Clinical characteristics of clear cell carcinoma of the ovary: a distinct histologic type with poor prognosis and resistance to platinum-based chemotherapy / Cancer 88:2584~2589
Anglesio MS / 2011 / Clear cell carcinoma of the ovary: a report from the first Ovarian Clear Cell Symposium, June 24th, 2010 / Gynecol Oncol 121:407~415
Oncology Committee of Japan Society of Obstetrics / 2010 / Annual report of the patients with ovarian cancers / Acta Obstet Gynaecol Jpn 62:827~910
Winter WE 3rd / 2007 / Prognostic factors for stage III epithelial ovarian cancer: a Gynecologic Oncology Group Study / J Clin Oncol 25:3621~3627
Sugiyama T / 2000 / Clinical characteristics of clear cell carcinoma of the ovary: a distinct histologic type with poor prognosis and resistance to platinum-based chemotherapy / Cancer 88:2584~2589
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