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논문 기본 정보

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학술저널
저자정보
Chun-Chi Lin (Taipei Veterans General Hospital) Shu-Chen Wei (National Taiwan University Hospital) Been-Ren Lin (National Taiwan University Hospital) Wen-Sy-Tsai (Chang Gung Memorial Hospital at Linkou) Jinn-Shiun Chen (Chang Gung Memorial Hospital at Linkou) Tzu-Chi Hsu (Mackay Memorial Hospital) Wei-Chen Lin (Mackay Memorial Hospital) Tien-Yu Huang (Tri-Service General Hospital) Te-Hsin Chao (Taichung Veterans General Hospital) Hung-Hsin Lin (Taipei Veterans General Hospital) Jau-Min Wong (National Taiwan University Hospital) Jen-Kou Lin (Taipei Veterans General Hospital)
저널정보
대한장연구학회 Intestinal research Intestinal research Vol.14 No.3
발행연도
2016.1
수록면
248 - 257 (10page)

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Background/Aims: With the recent progress in medical treatment, surgery still plays a necessary and important role in treatingulcerative colitis (UC) patients. In this study, we analyzed the surgical results and outcomes of UC in Taiwan in the recent20 years, via a multi-center study through the collaboration of Taiwan Society of IBD. Methods: A retrospective analysis ofsurgery data of UC patients from January 1, 1995, through December 31, 2014, in 6 Taiwan major medical centers was conducted. The patients’ demographic data, indications for surgery, and outcome details were recorded and analyzed. Results:The data of 87 UC patients who received surgical treatment were recorded. The median post-operative follow-up duration was51.1 months and ranged from 0.4 to 300 months. The mean age at UC diagnosis was 45.3±16.0 years and that at operation was48.5±15.2 years. The 3 leading indications for surgical intervention were uncontrolled bleeding (16.1%), perforation (13.8%),and intractability (12.6%). In total, 27.6% of surgeries were performed in an emergency setting. Total or subtotal colectomy withrectal preservation (41.4%) was the most common operation. There were 6 mortalities, all due to sepsis. Emergency operationand low pre-operative albumin level were significantly associated with poor survival (P =0.013 and 0.034, respectively). Conclusions: In the past 20 years, there was no significant change in the indications for surgery in UC patients. Emergencysurgeries and low pre-operative albumin level were associated with poor survival. Therefore, an optimal timing of elective surgeryfor people with poorly controlled UC is paramount.

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참고문헌 (47)

참고문헌 신청
Wilks S / 1859 / Morbid appearances in the intestines of Miss Banks / Med Times Gazette 2:264~265 google schola Loftus EV, Jr / 2004 / Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences / Gastroenterology 126:1504~1517 google schola Kornbluth A / 2010 / Ulcerative colitis practice guidelines in adults: American College Of Gastroenterology, Practice Parameters Committee / Am J Gastroenterol 105:501~523 google schola Sandborn WJ / 2003 / Systematic review: the pharmacokinetic profiles of oral mesalazine formulations and mesalazine pro-drugs used in the management of ulcerative colitis / Aliment Pharmacol Ther 17:29~42 google schola Desreumaux P / 2006 / Review article: mode of action and delivery of 5-aminosalicylic acid - new evidence / Aliment Pharmacol Ther 24(Suppl 1):2~9 google schola

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