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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 653 - 665 (13page)
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Liver failure is one of the main risks of death worldwide, and it originates from repetitive injuries and inflammations of liver tissues, which finally leads to the liver cirrhosis or cancer. Currently, liver transplantation is the only effective treatment for the liver diseases although it has a limitation due to donor scarcity. Alternatively, cell therapy to regenerate and reconstruct the damaged liver has been suggested to overcome the current limitation of liver disease cures. Several transplantable cell types could be utilized for recovering liver functions in injured liver, including bone marrow cells, mesenchymal stem cells, hematopoietic stem cells, macrophages, and stem cell-derived hepatocytes. Furthermore, paracrine effects of transplanted cells have been suggested as a new paradigm for liver disease cures, and this application would be a new strategy to cure liver failures. Therefore, here we reviewed the current status and challenges of therapy using stem cells for liver disease treatments.
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참고문헌 (3)
참고문헌 신청
정재민 / 2016 / Functional Comparison of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells as Sources of Hepatocyte-Like Cells / 조직공학과 재생의학 13(6):740~749
장유진 / 2017 / Identification of MFGE8 in mesenchymal stem cell secretome as an anti-fibrotic factor in liver fibrosis / BMB Reports 50(2):58~59
장윤옥 / 2015 / Inhibition of hepatic stellate cells by bone marrow-derived mesenchymal stem cells in hepatic fibrosis / Clinical and Molecular Hepatology 21(2):141~149
장유진 / 2017 / Identification of MFGE8 in mesenchymal stem cell secretome as an anti-fibrotic factor in liver fibrosis / BMB Reports 50(2):58~59
장윤옥 / 2015 / Inhibition of hepatic stellate cells by bone marrow-derived mesenchymal stem cells in hepatic fibrosis / Clinical and Molecular Hepatology 21(2):141~149
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