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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아혈액종양학회 Clinical Pediatric Hematology-Oncology Clinical Pediatric Hematology-Oncology Vol.24 No.2
- 발행연도
- 2017.1
- 수록면
- 162 - 168 (7page)
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초록· 키워드
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Ewing sarcoma/primitive neuroectodermal tumors (ES/PNET) are a group of malignant tumors with varying degrees of neuroectodermal differentiation. Although it may develop in any organs, ES/PNET originating from small intestine is exceedingly rare. We experienced a 9-year-old girl presenting with abdominal pain, melena, and iron deficiency anemia. Imaging work-up showed multiple masses in the small bowel and omentum with disseminated peritoneal seeding nodules, indicating lymphoma as the most likely diagnosis. Pathological reports from explorative diagnostic laparoscopic biopsy showed tumors comprising small round cells with CD99 expression and EWS-FLI1 translocation leading to the diagnosis of ES/PNET. Tumor burden decreased gradually during five consecutive cycles of systemic chemotherapy. The patient received segmental resection of jejunum, followed by adjuvant chemotherapy. This is the first pediatric case of ES/PNET found in small intestine in Korea.
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참고문헌 (15)
참고문헌 신청
Ludwig JA / 2008 / Ewing sarcoma: historical perspectives, current state-of-the-art, and opportunities for targeted therapy in the future / Curr Opin Oncol 20:412~418
Javery O / 2011 / A to Z of extraskeletal Ewing sarcoma family of tumors in adults: imaging features of primary disease, metastatic patterns, and treatment responses / AJR Am J Roentgenol 197:W1015~W1022
김준미 / 2013 / Peripheral Primitive Neuroectodermal Tumor with Osseous Component of the Small Bowel Mesentery: A Case Study / Journal of Pathology and Translational Medicine 47(1):77~81
Bernstein M / 2006 / Ewing's sarcoma family of tumors: current management / Oncologist 11:503~519
de Alava E / 2000 / Molecular biology of the Ewing's sarcoma/primitive neuroectodermal tumor family / J Clin Oncol 18:204~213
Javery O / 2011 / A to Z of extraskeletal Ewing sarcoma family of tumors in adults: imaging features of primary disease, metastatic patterns, and treatment responses / AJR Am J Roentgenol 197:W1015~W1022
김준미 / 2013 / Peripheral Primitive Neuroectodermal Tumor with Osseous Component of the Small Bowel Mesentery: A Case Study / Journal of Pathology and Translational Medicine 47(1):77~81
Bernstein M / 2006 / Ewing's sarcoma family of tumors: current management / Oncologist 11:503~519
de Alava E / 2000 / Molecular biology of the Ewing's sarcoma/primitive neuroectodermal tumor family / J Clin Oncol 18:204~213
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