지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 115 - 120 (6page)
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초록· 키워드
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Objectives: Bone loss after bariatric surgery is well recognized but the best method for quantifying bone mineral density (BMD) remains controversial. BMD measured with dual energy X-ray absorptiometry (DXA) is prone to measurement errors in this population while quantitative computed tomography (QCT) is less affected. We report the skeletal changes after bariatric surgery at 1-year in a multi-ethnic Asian cohort using both central DXA and QCT. Methods: Areal BMD (aBMD) and volumetric BMD (vBMD) of twenty-two participants (mean age 40.6; female 59%) undergoing sleeve gastrectomy (n ¼ 12) or gastric bypass (n ¼ 10) were measured with central DXA and QCT respectively before and 12-months after surgery. Results: Weight and BMI decreased significantly but discordant QCT and DXA results were noted. aBMD was significantly reduced at the total hip (TH) and femoral neck (FN) by 6.9 and 8.5% respectively but was not significantly different at the lumbar spine (LS). By contrast, there were no significant changes in vBMD at TH and FN. Instead, a significant 11.2% decrease in vBMD was noted at the LS. These findings were largely similar between the two surgical subgroups. Interestingly, cortical vBMD increased at both TH and FN while trabecular vBMD decreased at the TH. These changes were observed despite no significant post-operative changes in serum calcium, iPTH or 25-OH vitamin D levels. Conclusion: Technical or physiological factors may be involved in the discordance between QCT and DXA results during short-term follow-up and the most suitable method of bone density measurement for post-bariatric surgery patients remains uncertain. © 2015 The Korean Society of Osteoporosis. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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참고문헌 (37)
참고문헌 신청
Epidemiology SMoH / 2011 / National health survey 2010
Finucane MM / 2011 / National, regional, and global trends in body-mass index since 1980:systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9$1 million participants / Lancet 377:557~567
Group LAR / 2013 / Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes / N Engl J Med 369:145~154
Buchwald H / 2009 / Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis / Am J Med 122:248~256
Lee PC / 2013 / Impact of bariatric surgery on the management of type 2 diabetes mellitus in Singapore / Singap Med J 54:382~38v
Finucane MM / 2011 / National, regional, and global trends in body-mass index since 1980:systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9$1 million participants / Lancet 377:557~567
Group LAR / 2013 / Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes / N Engl J Med 369:145~154
Buchwald H / 2009 / Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis / Am J Med 122:248~256
Lee PC / 2013 / Impact of bariatric surgery on the management of type 2 diabetes mellitus in Singapore / Singap Med J 54:382~38v
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