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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 1,273 - 1,278 (6page)
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초록· 키워드
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This study was conducted to determine clinical parameters predicting future major adverse cardiovascular events (MACEs) in patients without significant stenosis on coronary computed tomographic angiography (CCTA). A total of 625 patients with suspected coronary artery disease (CAD) who underwent CCTA that revealed insignificant (< 50%) CAD was reviewed in three cardiac centers. The MACEs including cardiac death, non-fatal myocardial infarction (MI), unstable angina and late (> 90 days after CCTA) revascularization were assessed. During the mean follow-up period of 819 ± 529 days (median 837 days), there were 28 cases of MACEs (4.5%). In multivariable Cox regression analysis, independent predictors for MACEs were male sex (hazard ratio [HR], 2.40; 95% confidence interval [CI], 1.01-5.69; P = 0.046) and low estimated creatinine clearance (eCCr) (< 60 mL/min/1.73 m2) (HR, 3.07; 95% CI, 1.22-7.74; P = 0.017). Low eCCr was the only independent predictor for hard events including cardiac death and MI (HR, 17.6, 95% CI, 1.44-215.7; P = 0.025). In conclusion, renal function is an independent predictor for cardiovascular events among patients without significant CAD by CCTA. Careful monitoring and preventive strategy are warranted in patients with impaired renal function even without significant CAD.
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참고문헌 (30)
참고문헌 신청
Meijboom WB / 2008 / Diagnostic accuracy of 64-slice computed tomography coronary angiography: a prospective, multicenter, multivendor study / J Am Coll Cardiol 52:2135~2144
Miller JM / 2008 / Diagnostic performance of coronary angiography by 64-row CT / N Engl J Med 359:2324~2336
Budoff MJ / 2008 / Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease : results from the prospective multicenter ACCURACY(Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography)trial / J Am Coll Cardiol 52:1724~1732
Min JK / 2011 / Age- and sex-related differences in all-cause mortality risk based on coronary computed tomography angiography findings results from the International Multicenter CONFIRM (Coronary CT Angiography Evaluation for Clinical Outcomes: An International Multicenter Registry) of 23,854 patients without known coronary artery disease / J Am Coll Cardiol 58:849~860
Min JK / 2007 / Prognostic value of multidetector coronary computed tomographic angiography for prediction of all-cause mortality / J Am Coll Cardiol 50:1161~1170
Miller JM / 2008 / Diagnostic performance of coronary angiography by 64-row CT / N Engl J Med 359:2324~2336
Budoff MJ / 2008 / Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease : results from the prospective multicenter ACCURACY(Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography)trial / J Am Coll Cardiol 52:1724~1732
Min JK / 2011 / Age- and sex-related differences in all-cause mortality risk based on coronary computed tomography angiography findings results from the International Multicenter CONFIRM (Coronary CT Angiography Evaluation for Clinical Outcomes: An International Multicenter Registry) of 23,854 patients without known coronary artery disease / J Am Coll Cardiol 58:849~860
Min JK / 2007 / Prognostic value of multidetector coronary computed tomographic angiography for prediction of all-cause mortality / J Am Coll Cardiol 50:1161~1170
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