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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 117 - 124 (8page)
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Purpose: To evaluate the perioperative, functional, and oncological outcomes of renal cryoablation (RC) of small renal masses(SRMs) performed in Korea University Hospital.
Materials and Methods: We reviewed an Institutional Review Board-approved database of 70 patients who underwent RC andwere followed up for a minimum of 3 months by a single surgeon in Korea University Hospital from August 2007 to May 2014.
Among these patients, 68 patients (79 renal masses) were enrolled in our research. We evaluated perioperative, functional, and oncologicoutcomes of RC.
Results: A total of 68 patients (79 renal masses) underwent RC in our institution. The mean age of the patients was 62.0 years. Themean tumor size was 2.25 cm. Among the 59 patients who underwent laparoscopic surgery, only 1 patient (1.47%) was convertedto open surgery. No other perioperative complications occurred. The mean preoperative and 1-month postoperative estimatedglomerular filtration ratio (eGFR) were 71.8 and 68.3 mL/min/1.73 m2, respectively (p=0.19). The mean 1-year postoperative eGFRwas 65.0 mL/min/1.73 m2 (p=0.25). The mean follow-up period was 59.76 months (range, 3–119 months). Local tumor recurrenceoccurred in eight tumors (15.4%; a total of 52 renal cell carcinomas). Concerning treatment in the patients with recurrence, five patientsunderwent re-treatment and three patients are under active surveillance. None of the eight patients who experienced localrecurrence had additional recurrence or tumor progression during the follow-up period. In our study, the recurrence-free rate was83.0% and the cancer-specific survival rate was 100%. Moreover, the 5- and 10-year overall survival rates were both 100%.
Conclusions: Long-term experience with RC in our institution demonstrates that RC is a safe and effective treatment for patientswith SRMs.
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참고문헌 (25)
참고문헌 신청
정규원 / 2014 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2011 / Cancer Research and Treatment 46(2):109~123
Miller DC / 2010 / Contemporary clinical epidemiology of renal cell carcinoma: insight from a population based case-control study / J Urol 184:2254~2258
Campbell SC / 2009 / Guideline for management of the clinical T1 renal mass / J Urol 182:1271~1279
Kim SP / 2013 / The relationship of postoperative complications with in-hospital outcomes and costs after renal surgery for kidney cancer / BJU Int 111:580~588
Klatte T / 2011 / Laparoscopic cryoablation versus partial nephrectomy for the treatment of small renal masses: systematic review and cumulative analysis of observational studies / Eur Urol 60:435~443
Miller DC / 2010 / Contemporary clinical epidemiology of renal cell carcinoma: insight from a population based case-control study / J Urol 184:2254~2258
Campbell SC / 2009 / Guideline for management of the clinical T1 renal mass / J Urol 182:1271~1279
Kim SP / 2013 / The relationship of postoperative complications with in-hospital outcomes and costs after renal surgery for kidney cancer / BJU Int 111:580~588
Klatte T / 2011 / Laparoscopic cryoablation versus partial nephrectomy for the treatment of small renal masses: systematic review and cumulative analysis of observational studies / Eur Urol 60:435~443
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