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자료유형
학술저널
저자정보
저널정보
대한주산의학회 Perinatology Perinatology Vol.26 No.1
발행연도
2015.1
수록면
35 - 45 (11page)

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Objective: The aim of this study was to determine the incidence, risk factors, and long-term outcome ofnephrocalcinosis in very low birth weight (VLBW) infants. Methods: A retrospective chart review was performed in VLBW infants between 2006 and 2012 in theneonatal intensive care unit. Results: The incidence of nephrocalcinosis in VLBW infants was 10.2%. By univariate analysis,oligohydramnios and use of antenatal steroids were more frequent in the nephrocalcinosis group. In thenephrocalcinosis group, the gestational age and birth weight were lower and there were more number offemale infants. Also, the initial blood pH, the lowest systolic blood pressure, and urine output on the first day oflife were lower and bronchopulmonary dysplasia, sepsis, and urinary tract infection were more prevalent in thenephrocalcinosis group. The use of dexamethasone or ibuprofen and the lowest levels of phosphorus, proteinand albumin were significantly lower in the nephrocalcinosis group. By binary logistic regression analysis, theuse of antenatal steroids, female sex, 5-minute Apgar score, duration of oxygen therapy and total parenteralnutrition, and the lowest albumin level were found to be significant risk factors for nephrocalcinosis. Overall,the resolution rate was 64.1% and 88.6% within 12 months and 18 months, respectively. Conclusions: The incidence of nephrocalcinosis in VLBW infants showed increasing trend. The risk factorsof nephrocalcinosis were parameters for sick VLBW infants. Although the prognosis of nephrocalcinosis wasrelatively good, we should pay close attention to the development of complication.

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