지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 18 - 27 (10page)
이용수
초록· 키워드
오류제보하기
Background and Objectives：Many kinds of inflammatory cells and cytokines are suggested to be related to the pathophysiology of chronic rhinosinusitis with nasal polyposis (CRSwNP), but not yet fully understood. The objectives of this study were to classify CRSwNP patients according to histologic features and to reveal the roles of IL-33 and IL-25, on the pathophysiology of CRSwNP. Materials and Method：CRSwNP patients (n=122) were divided into 3 groups according to the type of nasal polyp; eosinophilic polyp (EP, n=38), neutrophilic polyp (NeuP, n=15) and non-eosinophilic non-neutrophilic polyp (NENN, n=63) groups. Clinical features and the expressions of IL-25 and IL-33 were evaluated among the groups. Results：The EP group showed many clinical features that were different from the other groups: increased prevalence of asthma and olfactory dysfunction, increased percentage of blood eosinophils, increased E/M ratio, and poor postoperative outcomes such as recurrent polyposis and the need for frequent use of oral steroids. Numbers of IL-33 and IL-25 positive cells were significantly higher in the EP group compared with the other groups in the lamina propria (p=0.001). Conclusion：These results suggest that patients with an eosinophilic polyp are clinically and pathogenetically different from patients with other types of polyps, and IL-25 and IL-33 are associated with the pathogenesis of chronic rhinosinusitis with eosinophilic polyps.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Enhanced Type 2 Immune Reactions by Increased IL-22/IL-22Ra1 Signaling in Chronic Rhinosinusitis With Nasal Polyps
Allergy, Asthma & Immunology Research
2020 .01
-
Role of IL-17A in Chronic Rhinosinusitis With Nasal Polyp
Allergy, Asthma & Immunology Research
2020 .01
-
Distinct Inflammatory Profiles in Atopic and Nonatopic Patients With Chronic Rhinosinustis Accompanied by Nasal Polyps in Western China
Allergy, Asthma & Immunology Research
2015 .01
-
비용종을 동반한 만성 비부비동염 치료에서 생물학적 제제의 최신 지견
대한이비인후-두경부외과학회지
2021 .10
-
Interleukin-10 발현 B 세포가 만성 비부비동염의 병태생리에 미치는 영향
대한이비인후-두경부외과학회지
2018 .01
-
A Potential Role of Group 2 Innate Lymphoid Cells in Eosinophilic Chronic Rhinosinusitis With Nasal Polyps
Allergy, Asthma & Immunology Research
2021 .01
-
IL-24 Contributes to Neutrophilic Asthma in an IL-17A-Dependent Manner and Is Suppressed by IL-37
Allergy, Asthma & Immunology Research
2022 .09
-
MCC950에 의한 Lipopolysaccharide로 유도된 Interleukin-1beta 발현 제어Dispersed Nasal Polyp Cells에서 Nucleotide-Binding Oligomerization Domain-Like Receptor 3 Inflammasone 억제 가능성에 대한 연구
대한이비인후-두경부외과학회지
2020 .01
-
비용종을 동반한 만성 비부비동염의 바이오마커: 내재형에 기초한 맞춤의료
대한이비인후-두경부외과학회지
2019 .01
-
비용종을 동반한 만성 비부비동염의 치료로서 생물학적 제제의 효과
임상이비인후과
2022 .06
-
IL-1 Receptor Dynamics in Immune Cells: Orchestrating Immune Precision and Balance
Immune Network
2024 .06
-
한국 환자를 대상으로 한 비용종이 있는 호산구 및 중성구성 만성 비부비동염의 임상적 특징 및치료 후 예후 분석
대한이비인후-두경부외과학회지
2024 .06
-
Association of Single Nucleotide Polymorphisms in Interleukin-12 Receptor (IL-12Rβ1 and IL-12Rβ2) with Asthma in a Korean Population
대한의생명과학회지
2020 .12
-
Interpretation of Clinical Efficacy of Biologics in Chronic Rhinosinusitis With Nasal Polyps via Understanding the Local and Systemic Pathomechanisms
Allergy, Asthma & Immunology Research
2022 .09
-
Expression of Il4rα and Il13rα1 in Gallbladder Cancer
대한외과학회 학술대회 초록집
2021 .11
-
I-Kappa-B-Zeta Regulates Interleukin-17A/Tumor Necrosis Factor-Alpha Mediated Synergistic Induction of Interleukin-19 and Interleukin-20 in Humane Keratinocytes
Annals of Dermatology
2021 .01
-
Relationship of Microbial Profile With Airway Immune Response in Eosinophilic or Neutrophilic Inflammation of Asthmat
Allergy, Asthma & Immunology Research
2020 .01
-
Endotype of Eosinophilic Nasal Polyposis According to the Presence of Atopy
대한이비인후-두경부외과학회지
2020 .01
-
Effect of scaling and root planing on the expression of anti-inflammatory cytokines (IL-4, IL-9, IL-10, and IL-13) in the gingival crevicular fluid of electronic cigarette users and non-smokers with moderate chronic periodontitis
Journal of Periodontal & Implant Science
2020 .01
-
Induction of Unique STAT Heterodimers by IL-21 Provokes IL-1RI Expression on CD8+ T Cells, Resulting in Enhanced IL-1β Dependent Effector Function
Immune Network
2021 .10
이 논문의 저자 정보
최근 본 자료
댓글(0)
0