지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.12
- 수록면
- 350 - 361 (12page)
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초록· 키워드
오류제보하기
Asarum sieboldii has been used for treatment of fever, pain, common cold, and chronic sinusitis in Korea. In this study, we performed quantification analysis of seven major constituents including aristolochic acid I, aristolochic acid II, α-asarone, β-asarone, elemicin, methyl eugenol, and safrole in the 70% ethanol extract of Asarum sieboldii and its solvent fractions, n-hexane, ethylacetate, n-butanol, and water ones using a ultra-performance liquid chromatography-electrospray ionizationmass spectrometer(UPLC-ESI-MS) and gas chromatography-mass spectrometer(GC-MS). Regression equations of seven components were acquired with r² values >0.99. The values of limit of detection(LOD) and quantification(LOQ) were 0.1-3.9 ng/mL and 0.3-11.7 mg/mL, respectively. The amount of the seven compounds in Asarum sieboldii were not detected -143.66 mg/g. The established LC-MS/MS and GC-MS methods will be helpful to improve quality control of Asarum sieboldii.
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참고문헌 (14)
참고문헌 신청
생약학교재편찬위원회 / 2012 / 생약학 / 동명사 :151~153
Lee, J. A. / Asiasari sieboldii suppresses inflammatory mediators through the induction of hemeoxygenase-1 expression in RAW264.7 cells / Immunopharmacol. Immunotoxicol 34:15~20
Han, Y. / 2003 / Memory enhancing of Asiasari Radix extracts via activation of insulin receptor and extracellular signal regulated kinase (ERK) I/II in rat hippocampus / Brain Res 974:193~201
Han. Y. / 2003 / Protection of brain cells against AMPA-induced damage by Asiasari Radix extracts / Phytother. Res 17:882~886
Oh, S. M. / 2013 / Anticancer potential of an ethanol extract of Asiasari Radix against HCT-116 human colon cancer cells in vitro / Oncol. Lett 5:305~310
Lee, J. A. / Asiasari sieboldii suppresses inflammatory mediators through the induction of hemeoxygenase-1 expression in RAW264.7 cells / Immunopharmacol. Immunotoxicol 34:15~20
Han, Y. / 2003 / Memory enhancing of Asiasari Radix extracts via activation of insulin receptor and extracellular signal regulated kinase (ERK) I/II in rat hippocampus / Brain Res 974:193~201
Han. Y. / 2003 / Protection of brain cells against AMPA-induced damage by Asiasari Radix extracts / Phytother. Res 17:882~886
Oh, S. M. / 2013 / Anticancer potential of an ethanol extract of Asiasari Radix against HCT-116 human colon cancer cells in vitro / Oncol. Lett 5:305~310
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UCI(KEPA) : I410-ECN-0101-2023-518-000068145