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논문 기본 정보

자료유형
학술저널
저자정보
Ruizhi Tao (Nanjing University of Chinese Medicine) Keqin Lu (Nanjing University of Chinese Medicine) Gangfan Zong (Nanjing University of Chinese Medicine) Yawen Xia (Nanjing University of Chinese Medicine) Hongkuan Han (Nanjing University of Chinese Medicine) Yang Zhao (Nanjing University of Chinese Medicine) Zhonghong Wei (Nanjing University of Chinese Medicine) Yin Lu (Nanjing University of Chinese Medicine)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.47 No.1
발행연도
2023.1
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9 - 22 (14page)

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초록· 키워드

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As a famous herbal medicine in China and Asia, ginseng (Panax ginseng C. A. Meyer) is also known as the "King of All Herbs" and has long been used in medicine and healthcare. In addition to the obvious biological activities of ginsenosides, ginseng polysaccharides (GPs) exhibit excellent antitumor, antioxidant stress, and immunomodulatory effects. In particular, GPs can exert an antitumor effect and is a potential immunomodulator. However, due to the complexity and diversity in the structures and components of GPs, their specific physicochemical properties, and underlying mechanisms remain unclear. In this article, we have summarized the factors influencing the antitumor activity of GPs and their mechanism of action, including the stimulation of the immune system, regulation of the gut microbiota, and direct action on tumor cells

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ABSTRACT
1. Introduction
2. Antitumor potential of GPs in clinical settings
3. Effects of the physicochemical properties of GPs on their antitumor activities
4. Mechanisms underlying the antitumor effects of GPs
5. Conclusions and perspectives
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