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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.2
- 수록면
- 159 - 174 (16page)
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초록· 키워드
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Memory T (Tm) cells protect against Ags that they have previously contacted with a fast and robust response. Therefore, developing long-lived Tm cells is a prime goal for many vaccines and therapies to treat human diseases. The remarkable characteristics of Tm cells have led scientists and clinicians to devise methods to make Tm cells more useful. Recently, Tm cells have been highlighted for their role in coronavirus disease 2019 vaccines during the ongoing global pandemic. The importance of Tm cells in cancer has been emerging. However, the precise characteristics and functions of Tm cells in these diseases are not completely understood. In this review, we summarize the known characteristics of Tm cells and their implications in the development of vaccines and immunotherapies for human diseases. In addition, we propose to exploit the beneficial characteristics of Tm cells to develop strategies for effective vaccines and overcome the obstacles of immunotherapy.
목차
ABSTRACT
INTRODUCTION
CARDINAL FEATURES OF Tm CELLS
MEMORY CD8+ T CELLS AS KEY DRIVERS FOR IMMUNOTHERAPY AND VACCINE
APPLICATION OF MEMORY CD8+ T CELLS AS IMMUNOTHERAPY AND VACCINE
CONCLUSION AND FUTURE PERSPECTIVES
REFERENCES
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UCI(KEPA) : I410-ECN-0101-2023-517-000427278