Genome-wide locus-specific DNA methylation repatterning may facilitate rapid evolution of mercury resistance in rice

Cong Weixuan; Li Ning; Wang Jinbin; Kang Ying; Miao Yiling; Xu Chunming; Wang Ziqi; Liu Tongtong; Gong Lei; Liu Bao; Ou Xiufang

doi:10.1007/s13258-021-01192-y

Genome-wide locus-specific DNA methylation repatterning may facilitate rapid evolution of mercury resistance in rice

Recommendations

Search

Type: Academic journal

Author: Cong Weixuan (Northeast Normal University China) Li Ning (Northeast Normal University China) Wang Jinbin (Northeast Normal University China) Kang Ying (Northeast Normal University China) Miao Yiling (Northeast Normal University China) Xu Chunming (Northeast Normal University China) Wang Ziqi (Northeast Normal University China)

Journal: 한국유전학회 Genes & Genomics Genes & Genomics Vol.44 No.3 KCI Accredited Journals

Published: 2022.3

Pages: 299 - 306 (8page)

DOI: 10.1007/s13258-021-01192-y

Usage

Genome-wide locus-specific DNA methylation repatterning may facilitate rapid evolution of mercury resistance in rice

Abstract· Keywords

Report Errors

Background Albeit a relatively stable epigenetic modification, DNA methylation in plants can be repatterned and play important roles in response to biotic and abiotic stresses. However, whether DNA methylation dynamics may contribute to cope with mercury (Hg) stress in plants remains to be fully investigated. Objective To probe the potential roles of DNA methylation dynamics in coping with Hg stress in rice. Methods Whole-genome bisulfite sequencing was used to profile the DNA methylation patterns of a rice Hg-resistant line (RHg) selected from a heterozygous mutant of the DNA methyltransferase 1 gene (OsMET1+/?), together with its Hg-sensitive wild-type plants of cv. Nipponbare (Nip) under both normal and Hg stress conditions. Results Genome-wide locus-specific differential methylation regions (DMRs) were detected between RHg and Nip under normal condition, the predominant DMR patterns were CG hypo-DMRs, CHG hypo-DMRs and CHH hyper-DMRs. In both lines, more hyper- than hypo-DMRs were detected at all three sequence contexts (CG, CHG and CHH) under Hg stress relative to normal condition. Comparison of DNA methylation changes in the two lines under Hg stress indicates that RHg had a more dynamic methylome than the control (Nip). Original DMRs in RHg trended to transform to opposite status (from hyper- to hypo- or vice versa) under Hg stress condition. Gene ontology analysis revealed that Hg-resistance-related DMGs were enriched in diverse biological processes. Conclusions Our results suggest genome-wide locus-specific DNA methylation repatterning can facilitate rapid acquisition of Hg resistance in rice.

#Mercury stress · DNA methylation · DMRs · DMGs · Rice

No content found

References (0)

Add References

If the reference is being serviced by DBpia, please register through [Add Reference]

Recommendations

It is an article recommended by DBpia according to the article similarity. Check out the related articles!