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논문 기본 정보

자료유형
학술저널
저자정보
Lee Na-Kyoung (Department of Orthopaedic Surgery Seoul National University Bundang Hospital Seongnam Korea.) Won Samuel Jaeyoon (Department of Orthopaedic Surgery Seoul National University Bundang Hospital Seongnam Korea.) Lee Jun-Young (Department of Psychiatry Seoul Metropolitan Government-Seoul National University Boramae Medical Ce) Kang Seung-Baik (Department of Orthopaedic Surgery Seoul Metropolitan Government-Seoul National University Boramae M) Yoo So Young (Department of Psychiatry Seoul Metropolitan Government-Seoul National University Boramae Medical Ce) Chang Chong Bum (Department of Orthopaedic Surgery Seoul National University Bundang Hospital Seongnam Korea.Departm)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.37 No.43
발행연도
2022.11
수록면
1 - 12 (12page)
DOI
10.3346/jkms.2022.37.e309

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Background: A considerable proportion of patients warranting total knee arthroplasty (TKA) have night pain, neuropathic pain, and/or depressive disorder, which may not be resolved by TKA. This prospective, longitudinal cohort study aimed to document the prevalence of night pain, neuropathic pain, and depressive disorder in patients with advanced knee osteoarthritis undergoing TKA and to determine whether the specific coexisting pain and/or disorder at the time of TKA adversely affected postoperative outcomes. Methods: In this study, 148 patients undergoing TKA were longitudinally evaluated. The presence of night pain, neuropathic pain (determined using Douleur Neuropathique 4 [DN4]) and depressive disorder (determined using the Patient Health Questionnaire-9 [PHQ-9]) was determined before and 6 weeks, 3 months and 1 year after TKA. In addition, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and EuroQol-5 Dimension (EQ-5D) scores were assessed before and 1 year after TKA. Potential associations of night pain, neuropathic pain, and/or depressive disorder with pre- and postoperative WOMAC and EQ-5D scores were examined in subgroup analyses. Results: Preoperatively, 72% (n = 106) of patients reported night pain, and the prevalences of neuropathic pain and depressive disorder were 15% and 17%, respectively. Preoperatively, compared with patients without night pain, those with night pain had significantly poorer preoperative WOMAC scores, but no significant difference was seen between groups 1 year after TKA. Preoperatively, the WOMAC, EQ-5D, and EQ-5D health scores of patients with neuropathic pain were not significantly different from those of patients without neuropathic pain, and there was no difference in clinical outcome scores 1 year after TKA between these groups. Preoperatively, the patients with depressive disorder showed significantly poorer preoperative WOMAC, EQ-5D, and EQ-5D health scores than those without depressive disorder, but no significant differences in scores were observed 1 year after TKA between these groups. Conclusion: This study revealed a considerable prevalence of night pain, neuropathic pain, and depressive disorder in patients undergoing TKA and that patients with these specific conditions reported poorer functional and quality of life scores preoperatively. However, such adverse effects disappeared after TKA. Our study findings suggest that TKA can provide satisfactory outcomes for patients with these specific conditions.
#Night Pain #Neuropathic Pain #Depressive Disorder #Total Knee Arthroplasty #Clinical Outcome

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