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논문 기본 정보

자료유형
학술저널
저자정보
Lee Seung-Jea (Department of Physiology College of Medicine Soonchunhyang University Cheonan 31151 KoreaDepartment) Kim Tae-Wook (Department of Physiology College of Medicine Soonchunhyang University Cheonan 31151 Korea) Park Tae-Hwan (Department of Physiology College of Medicine Soonchunhyang University Cheonan 31151 Korea) Lee In-Ho (Department of Occupational and Environmental Medicine Soonchunhyang University Cheonan Hospital Che) Jang Eun-Chul (Department of Occupational and Environmental Medicine Soonchunhyang University Cheonan Hospital Che) Kwon Soon-Chan (Department of Occupational and Environmental Medicine Soonchunhyang University Cheonan Hospital Che) Lee Hye-Jin (Department of Physiology College of Medicine Soonchunhyang University Cheonan 31151 KoreaDepartment) Choi Jeong-Hwan (Department of Medical Sciences Soonchunhyang University Asan 31238 Korea) 이정범 (순천향대학교)
저널정보
대한약리학회 The Korean Journal of Physiology & Pharmacology The Korean Journal of Physiology & Pharmacology 제26권 제6호
발행연도
2022.11
수록면
501 - 509 (9page)
DOI
10.4196/kjpp.2022.26.6.501

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Irisin is a myokine caused by exercise that improves insulin resistance and weight loss. However, under unfavorable conditions such as air pollution, and during the pandemic, outdoor activities are uncomfortable. Therefore, in this study, the effect of heat therapy (half bath 42 ± 0.5°C for 30 min) on irisin circulation levels as an exercise alternative for middle-aged obese women after menopause was investigated. Subjects were 33 women aged 49.54 ± 6.04 years, with parameters of height, 160.12 ± 4.33 cm, weight, 69.71 ± 7.52 kg, body surface area 1.73 ± 0.13 m2, body mass index, 27.19 ± 3.40 kg/m2. The results suggest that circulating irisin levels showed a significant increase after one-time thermotherapy (TH-1). However, the increase in circulating irisin levels after 15 treatments (TH-15, 5 days/week, 3 weeks) was significantly varied. The level of adiponectin, which increases fatty oxidation to reduce fatty deposition, increased significantly at TH-1, but further increased at TH- 15, which was significantly different from the level of TH-1. In addition, the basic serum free fatty acid (FFA) level was significantly increased at TH-15 compared to TH-1. Significant differences were also found in the lipid profile (body mass index, waist circumference, and % body fat). Thermotherapy can significantly increase the tympanic temperature and induce changes in circulating irisin and adiponectin levels. Thus, it resulted in positive changes in FFA and lipid profiles. Therefore, repeated thermotherapy is effective in increasing circulating irisin levels in postmenopausal obese women.

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