지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.7
- 수록면
- 333 - 350 (18page)
- DOI
- 10.3350/cmh.2021.0308
이용수
초록· 키워드
오류제보하기
The tumor microenvironment generally shows a substantial immunosuppressive activity in hepatocellular carcinoma (HCC), accounting for the suboptimal efficacy of immune-based treatments for this difficult-to-treat cancer. The crosstalk between tumor cells and various cell types in the tumor microenvironment is strongly related to HCC progression and treatment resistance. Monocytes are recruited to the HCC tumor microenvironment by various factors and become tumor-associated macrophages (TAMs) with distinct phenotypes. TAMs often contribute to weakened tumor-specific immune responses and a more aggressive phenotype of malignancy. Recent single-cell RNA-sequencing data have demonstrated the central roles of specific TAMs in tumorigenesis and treatment resistance by their interactions with various cell populations in the HCC tumor microenvironment. This review focuses on the roles of TAMs and the crosstalk between TAMs and neighboring cell types in the HCC tumor microenvironment.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Tumor-Associated Macrophages in Hepatocellular Carcinoma: Friend or Foe?
Gut and Liver
2021 .01
-
Role of notch signaling in tumor associated macrophages
한국실험동물학회 학술발표대회 논문집
2021 .07
-
Reprogramming the tumor microenvironment with biotechnology
생체재료학회지
2023 .03
-
How to explore tumor microenvironment in gastric cancer
대한임상종양학회 학술대회지
2022 .02
-
Spatial transcriptome analysis of tumor microenvironment
대한임상종양학회 학술대회지
2022 .02
-
Tumor landscape drawn from single cell RNA sequencing
한국실험동물학회 학술발표대회 논문집
2019 .01
-
Tumor microenvironment-responsive nanoparticles for cancer theragnostic applications
생체재료학회지
2018 .09
-
Immuno-oncology for B-cell lymphomas
Blood Research
2021 .04
-
Immuno-oncology for B-cell lymphomas
Blood Research
2021 .01
-
Role of Periostin in Hepatocellular Carcinoma: The Importance of Tumor Microenvironment
Gut and Liver
2016 .01
-
Tumor Cells and Cancer-Associated Fibroblasts: A Synergistic Crosstalk to Promote Thyroid Cancer
Endocrinology and Metabolism
2020 .01
-
Enriching CCL3 in the Tumor Microenvironment Facilitates T cell Responses and Improves the Efficacy of Anti-PD-1 Therapy
Immune Network
2021 .06
-
간세포암의 진단과 치료에서 종양표지자의 역할
대한내과학회지
2020 .02
-
DLK1 suppresses melanoma growth by shaping tumor immune microenvironment
한국실험동물학회 학술발표대회 논문집
2021 .07
-
Deciphering and Reversing Immunosuppressive Cells in the Treatment of Hepatocellular Carcinoma
Journal of Liver Cancer
2020 .01
-
Altered Biological Potential and Radioresponse of Murine Tumors in Different Microenvironments
Cancer Research and Treatment
2016 .01
-
Lymphopenia predicts reduced survival in canine hepatocellular carcinoma
Journal of Veterinary Science
2023 .05
-
Role of PD-1 expressed on regulatory T cells during cancer progression
한국실험동물학회 학술발표대회 논문집
2018 .01
-
Exosomal Communication Between the Tumor Microenvironment and Innate Immunity and Its Therapeutic Application
Immune Network
2022 .10
-
Cancer Microenvironment
대한외과학회 학술대회 초록집
2018 .11
이 논문의 저자 정보
최근 본 자료
댓글(0)
0