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논문 기본 정보

자료유형
학술저널
저자정보
Kim Do Yeon (Department of Neurology Seoul National University Bundang Hospital Seoul National University Colleg) Kang Jihoon (Department of Neurology Cerebrovascular Center Seoul National University Bundang Hospital Seoul Nat) Jeong Han-Gil (Division of Neurocritical Care Department of Neurosurgery and Neurology Seoul National University B) Park Chan-Young (Department of Neurology Seoul National University Bundang Hospital Seoul National University Colleg) Kim Jun Yup (Department of Neurology Cerebrovascular Center Seoul National University Bundang Hospital Seoul Nat) Kim Beom Joon (Department of Neurology and Cerebrovascular Disease Center Seoul National University Bundang Hospit) Han Moon-Ku (Department of Neurology Seoul National University Bundang Hospital Seoul National University Colleg) Bae Hee-Joon (Department of Neurology and Cerebrovascular Disease Center Seoul National University Bundang Hospit) Kim Baik Kyun (Department of Neurology Gyeonggi Provincial Medical Center Icheon Hospital Icheon Korea)
저널정보
대한신경집중치료학회 Journal of Neurocritical Care Journal of Neurocritical Care Vol.15 No.2
발행연도
2022.12
수록면
88 - 95 (8page)
DOI
10.18700/jnc.220063

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Background: Although atrial fibrillation (AF)-associated acute ischemic stroke (AIS) is on the rise, is devastating, and life-threatening, there is limited data on the clinical course and in-hospital mortality of patients treated in the intensive care unit (ICU). This study aimed to describe the clinical course and factors associated with in-hospital mortality in AF-associated AIS patients admitted to the ICU.Methods: This study was a retrospective analysis of a prospective nationwide multicenter cohort including non-valvular AF-AIS patients receiving ICU care admitted to 14 stroke centers in South Korea from 2017 to 2020. In-hospital outcomes, including in-hospital mortality and neurological deterioration (ND) have been described.Result: Amongst 2,487 AF-associated AIS patients, 259 (10.4%) were treated in the ICU. In-hospital mortality and ND occurred in 8.5% and 17.0% of the patients, respectively. Higher rates of initial National Institute for Health Stroke Scale scores, symptomatic steno-occlusive lesions, and CHA<sub>2</sub>DS<sub>2</sub>-VASc (Congestive Heart Failure, Hypertension, Age ≥75 [Doubled], Diabetes Mellitus, Prior Stroke or Transient Ischemic Attack [Doubled], Vascular Disease, Age 65–74, Female) scores were found in those with in-hospital mortality. The CHA<sub>2</sub>DS<sub>2</sub>-VASc score after admission increased the risk of in-hospital mortality (odds ratio [OR], 1.48; 95% confidence interval [CI], 1.00–2.18) were associated with in-hospital mortality. Antithrombotic use within 48 hours was related to decreased in-hospital mortality (OR, 0.26; 95% CI, 0.10–0.67).Conclusion: ICU care in AF-associated AIS is common, and the establishment of optimal treatment strategies in the ICU may be needed.

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