지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.4
- 수록면
- 1 - 11 (11page)
- DOI
- 10.1038/s12276-021-00604-z
이용수
초록· 키워드
오류제보하기
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the ongoing global outbreak of a coronavirus disease (herein referred to as COVID-19). Other viruses in the same phylogenetic group have been responsible for previous regional outbreaks, including SARS and MERS. SARS-CoV-2 has a zoonotic origin, similar to the causative viruses of these previous outbreaks. The repetitive introduction of animal viruses into human populations resulting in disease outbreaks suggests that similar future epidemics are inevitable. Therefore, understanding the molecular origin and ongoing evolution of SARS-CoV-2 will provide critical insights for preparing for and preventing future outbreaks. A key feature of SARS-CoV-2 is its propensity for genetic recombination across host species boundaries. Consequently, the genome of SARS-CoV-2 harbors signatures of multiple recombination events, likely encompassing multiple species and broad geographic regions. Other regions of the SARS-CoV-2 genome show the impact of purifying selection. The spike (S) protein of SARS-CoV-2, which enables the virus to enter host cells, exhibits signatures of both purifying selection and ancestral recombination events, leading to an effective S protein capable of infecting human and many other mammalian cells. The global spread and explosive growth of the SARS-CoV-2 population (within human hosts) has contributed additional mutational variability into this genome, increasing opportunities for future recombination.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Phylogenetic Relationship of the Complete SARS-CoV-2 Genome Sequences
한국생물공학회 학술대회
2020 .06
-
Pig Sera-derived Anti-SARS-CoV-2 Antibodies with Controlled Specificity for Competitive Immunoassay
한국생물공학회 학술대회
2021 .04
-
Development of Various Diagnostic tool of SARS-COV-2 Infection
한국생물공학회 학술대회
2020 .06
-
Competitive Immunoassay of SARS‑CoV‑2 Using Pig Sera‑Derived Anti‑SARS‑CoV‑2 Antibodies
BioChip Journal
2021 .01
-
SARS-CoV-2 Recovery from the Wastewater
한국생물공학회 학술대회
2022 .09
-
Detection of Severe Acute Respiratory Syndrome Coronavirus 2 Using Graphene-based Biosensor
한국생물공학회 학술대회
2021 .04
-
From bedside to bench: regulation of host factors in SARS-CoV-2 infection
Experimental and Molecular Medicine
2021 .04
-
Production of ACE2-derived Peptides in E. coli for the Inhibition of Spike Glycoprotein of SARS-CoV-2
한국생물공학회 학술대회
2021 .10
-
Isolation of?Antibodies Against the?Spike Protein of?SARS-CoV from?Pig Serum for?Competitive Immunoassay
BioChip Journal
2021 .12
-
SARS-CoV-2 Monitoring in Wastewater from Sewage Treatment Plants
한국생물공학회 학술대회
2022 .09
-
나노 소재를 이용한 SARS-CoV-2 검출 센서
기계저널
2021 .07
-
SARS-CoV, MERS-CoV, SARS-CoV-2 (COVID-19) 관련 뉴스 빅데이터 비교 분석
한국컴퓨터정보학회논문지
2021 .08
-
Mutational spectrum of SARS-CoV-2 during the global pandemic
Experimental and Molecular Medicine
2021 .08
-
Specific antigen assay to assist diagnosis of SARS-CoV-2 infection
한국생물공학회 학술대회
2020 .10
-
A Simple and Multiplex Loop-Mediated Isothermal Amplification (LAMP) Assay for Rapid Detection of SARS-CoV
BioChip Journal
2019 .01
-
Does SARS-CoV-2 affect neurodegenerative disorders? TLR2, a potential receptor for SARS-CoV-2 in the CNS
Experimental and Molecular Medicine
2022 .04
-
Development of a Multiplex Loop-mediated Isothermal Amplification (LAMP) Assay for On-site Diagnosis of SARS CoV-2
한국생물공학회 학술대회
2021 .04
-
공공하수처리시설 내 유입되는 SARS-CoV-2 바이러스의 source tracking을 위한 하수관거 모니터링 방법론 연구
대한토목학회 학술대회
2024 .10
-
Establishment of Potent Neutralizing Antibodies against SARS-CoV-2
한국생물공학회 학술대회
2021 .10
-
Development of a SARS-CoV-2-specific Biosensor for Antigen Detection Using scFv-Fc Fusion Proteins
한국생물공학회 학술대회
2021 .04
이 논문의 저자 정보
최근 본 자료
댓글(0)
0