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논문 기본 정보

자료유형
학술저널
저자정보
Somayeh Sadeghi (Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences,) Maryam Nasirian (Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences,) Elaheh Keivany (Isfahan University of Medical Sciences) Peiman Nasri (Isfahan University of Medical Sciences) Maryam Sadat Mirenayat (Shahid Beheshti University of Medical Sciences Tehran Iran)
저널정보
대한혈액학회 Blood Research Blood Research Vol.56 No.4
발행연도
2021.12
수록면
293 - 300 (8page)
DOI
10.5045/br.2021.2021131

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Background Since the emergence of coronavirus disease 2019 (COVID-19), various clinical manifestations ranging from asymptomatic to severe, life-threatening courses have been presented. It is well known that COVID-19 patients are at an increased risk of pulmonary thromboembolism (PTE) development; however, the associated demographic, medical, and clinical factors for developing PTE remain unknown. The current study aimed to assess the characteristics of patients with PTE. Methods This case-control study was derived from an ongoing population-based investigation of hospitalized patients with COVID-19 pneumonia. The case group included 99 patients with PTE confirmed by computed tomography pulmonary angiography (CTPA), and the controls (N=132) were age-matched patients selected from the PTE-suspected patients with a negative CTPA. The demographic, medical, and clinical characteristics of the study population were entered into the study checklist and compared. A logistic regression test was used to determine the factors associated with PTE development. Results Among the 13,099 admitted patients, 690 (5.26%) were suspected of having PTE according to their clinical manifestations. CTPA was performed for suspected cases, and PTE was confirmed in 132 patients (19.13%). Logistic regression assessments revealed that male gender (OR, 2.39; 95%CI, 1.38?4.13), decreased oxygen saturation (OR, 2.33; 95%CI, 1.27?4.26), and lower hemoglobin (OR, 0.83, 0.95), and albumin (OR, 0.31; 95%CI, 0.18?0.53) levels were associated with PTE development. Conclusion PTE was confirmed in one-fifth of suspected patients who underwent CTPA imaging. Male sex, decreased oxygen saturation, and lower levels of hemoglobin and albumin were independent predictors of PTE in patients with COVID-19 pneumonia.
#COVID-19 #Pulmonary embolism #Computed tomography angiography #Coronavirus

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참고문헌 (30)

참고문헌 신청
Guan WJ / 2020 / Clinical characteristics of coronavirus disease 2019 in China / N Engl J Med 382:1708~1720 google schola De Cobelli F / 2021 / Pulmonary vascular thrombosis in COVID-19 pneumonia / J Cardiothorac Vasc Anesth 35:3631~3641 google schola Abou-Ismail MY / 2020 / The hypercoagulable state in COVID-19 : incidence, pathophysiology, and management / Thromb Res 194:101~115 google schola Bikdeli B / 2020 / COVID-19 and thrombotic or thromboembolic disease : implications for prevention, antithrombotic therapy, and follow-up : JACC state-of-the-art review / J Am Coll Cardiol 75:2950~2973 google schola Beun R / 2020 / Thromboembolic events and apparent heparin resistance in patients infected with SARS-CoV-2 / Int J Lab Hematol 42(Suppl 1):19~20 google schola

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