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Predicting Factors of Severe COVID-19 in Patients With Asthma: A Korean National Cohort Study
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논문 기본 정보

Type
Academic journal
Author
Lee Hyun (Department of Internal Medicine Hanyang University College of Medicine Seoul Korea.) Hayoung Choi (한림대학교) Lee Sun-Kyung (Department of Internal Medicine Hanyang University College of Medicine Seoul Korea.Department of Ma) Park Tai Sun (Department of Internal Medicine Hanyang University College of Medicine Seoul Korea.)
Journal
대한천식알레르기학회(구 대한알레르기학회) Allergy, Asthma & Immunology Research Allergy, Asthma & Immunology Research Vol.13 No.6 KCI Accredited Journals
Published
2021.11
Pages
939 - 944 (6page)
DOI
10.4168/aair.2021.13.6.939

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Predicting Factors of Severe COVID-19 in Patients With Asthma: A Korean National Cohort Study
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Abstract· Keywords

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As there are limited data on the disease course of and factors predicting severe coronavirus disease 19 (COVID-19) in patients with asthma, this study aims to perform a detailed analysis of the clinical course of asthmatic patients with COVID-19 and evaluate factors related to severe infection. Of the 5,628 patients confirmed with COVID-19, 128 (2.3%) had asthma. Among the 128 asthmatic patients, 32 (25%) had severe COVID-19 and 96 (75%) had non-severe COVID-19. Among asthmatic patients, those with severe COVID-19 were significantly older and had more dyspnea and fever, more comorbidities, and lower lymphocyte and platelet counts than those with non-severe COVID-19. In multivariable logistic regression analysis, chronic obstructive pulmonary disease (adjusted odds ratio [aOR], 6.49; 95% confidence interval [CI], 1.18?41.81), low lymphocyte proportion (aOR, 0.91; 95% CI, 0.86?0.97), and low platelet count (aOR, 0.99; 95% CI, 0.98?0.99) were independently associated with severe COVID-19.
#Asthma #COVID-19 #chronic obstructive pulmonary disease

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References (11)

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Guan WJ / 2020 / Clinical characteristics of coronavirus disease 2019 in China / N Engl J Med 382:1708~1720 google schola Li X / 2020 / Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan / J Allergy Clin Immunol 146:110~118 google schola Lovinsky-Desir S / 2020 / Asthma among hospitalized patients with COVID-19 and related outcomes / J Allergy Clin Immunol 146:1027~1034 google schola Williamson EJ / 2020 / Factors associated with COVID-19-related death using OpenSAFELY / Nature 584:430~436 google schola Korea Disease Control and Prevention Agency (KDCA) google schola

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