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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.8
- 수록면
- 961 - 973 (13page)
- DOI
- 10.1007/s13258-021-01122-y
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초록· 키워드
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Background Recently, many researchers focus on the best way to produce high-quality meat, as the trend in food consumption today is to focus on quality. In general, consumers’ preferences in beef difer depending on taste and meatiness. Therefore, researchers are interested in how the marbling score afects the favors of meat or the various factors that make up the meatiness to captivate the consumers’ tastes.
Objective This study identifes single nucleotide polymorphisms (SNPs) or gene combinations that afect the carcass traits of Korean cattle (Hanwoo) by using the multifactor dimensionality reduction (MDR) method.
Methods We collected the candidate SNPs to identify SNPs related to marbling scores from whole-exome sequencing and bovine SNP genotyping data. Using 96 Hanwoo samples, we performed PCR amplifcation to investigate the polymorphism status. In addition, we investigated genetic relationships between carcass traits and SNPs using 612 Hanwoo samples. Furthermore, each candidate SNP genotype and the combinations of SNP genotypes were verifed to improve the accuracy of genetic relationships using MDR method.
Results Twenty-four candidate SNPs associated with carcass trait and marbling scores were identifed from SNP genotyping and whole-exome sequencing. Among them, three SNP markers (c.459 T>C of the PLCB1 gene, c.271 A>C of the C/EBPα gene, and g.17257 A>G of the TDRKH gene) were showed statistically signifcant diferences between intramuscular fat and genotypes. Especially, two candidate SNPs, including c.459 T>C located in the PLCB1 gene and c.271 A>C located in the C/ EBPα gene, could be highly associated with the intramuscular fat of Hanwoo quality grade. In addition, the combination of SNP genotypes is showed higher signifcant diferences with carcass weight, backfat thickness, and longissimus dorsi muscle area.
Conclusion Three SNP genotypes and the combination of SNP genotypes in the PLCB1, C/EBPα, and TDRKH genes may be useful genetic markers for improving beef quality.
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참고문헌 (16)
참고문헌 신청
Bastone L / 2004 / MDR and PRP : a comparison of methods for high-order genotype-phenotype associations / Hum Hered 58:82~92
Ki Yong Chung / 2018 / Current situation and future prospects for beef production in South Korea — A review / Animal Bioscience 31(7):951~960
Henderson CR / 1976 / A simple method for computing the inverse of a numerator relationship matrix used in prediction of breeding values / Biometrics 32:69~83
Jo C / 2012 / Keys to production and processing of Hanwoo beef : a perspective of tradition and science / Anim Front 2:32~38
Kim Do-Gyun / 2020 / Discrimination study between carcass yield and meat quality by gender in Korean native cattle (Hanwoo) / Animal Bioscience 33(7):1202~1208
Ki Yong Chung / 2018 / Current situation and future prospects for beef production in South Korea — A review / Animal Bioscience 31(7):951~960
Henderson CR / 1976 / A simple method for computing the inverse of a numerator relationship matrix used in prediction of breeding values / Biometrics 32:69~83
Jo C / 2012 / Keys to production and processing of Hanwoo beef : a perspective of tradition and science / Anim Front 2:32~38
Kim Do-Gyun / 2020 / Discrimination study between carcass yield and meat quality by gender in Korean native cattle (Hanwoo) / Animal Bioscience 33(7):1202~1208
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