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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.12
- 수록면
- 914 - 921 (8page)
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초록· 키워드
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Background and Objectives The purpose of this study was to systematically review literatureson active surveillance for low-risk differentiated thyroid cancer, and to evaluate risk factorsfor tumor size increase during active surveillance.
Subjects and Method We conducted a systematic review and a meta-analysis of studies reportingon tumor growth during active surveillance of papillary thyroid cancer. Using theMEDLINE and EMBASE databases, we searched studies published from the inception of databaseto December 2020. Studies were included if reported on at least one clinical risk parameterin addition to reporting on the change in tumor size during active surveillance.
Results Out of 33 studies screened, seven were included in the meta-analysis. The odds ratioof a temporal size increase of more than 3 mm in papillary thyroid cancer was 0.011 person-years (95% confidence interval [CI]: 0.009 to 0.013). The odds ratio of lymph node metastasiswas 0.002 person-years (95% CI: 0.001 to 0.003). Younger age was a significant riskfactor for tumor growth during active surveillance, with a standardized median difference of-0.63 (95% CI: -1.00 to -0.27). In the three studies that evaluated the association of thyroidstimulatinghormone levels and tumor size, the results were contradictory.
Conclusion Active surveillance may be used more cautiously for younger patients.
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참고문헌 (39)
참고문헌 신청
Canaris GJ / 2000 / The Colorado thyroid disease prevalence study / Arch Intern Med 160(4):526~534
정규원 / 2012 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2009 / Cancer Research and Treatment 44(1):11~24
Cho BY / 2013 / Changes in the clinicopathological characteristics and outcomes of thyroid cancer in Korea over the past four decades / Thyroid 23(7):797~804
Kent WD / 2007 / Increased incidence of differentiated thyroid carcinoma and detection of subclinical disease / CMAJ 177(11):1357~1361
Pathak KA / 2013 / The changing face of thyroid cancer in a population-based cohort / Cancer Med 2(4):537~544
정규원 / 2012 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2009 / Cancer Research and Treatment 44(1):11~24
Cho BY / 2013 / Changes in the clinicopathological characteristics and outcomes of thyroid cancer in Korea over the past four decades / Thyroid 23(7):797~804
Kent WD / 2007 / Increased incidence of differentiated thyroid carcinoma and detection of subclinical disease / CMAJ 177(11):1357~1361
Pathak KA / 2013 / The changing face of thyroid cancer in a population-based cohort / Cancer Med 2(4):537~544
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