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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.11
- 수록면
- 1 - 9 (9page)
- DOI
- 10.3346/jkms.2021.36.e271
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초록· 키워드
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Background: We conducted a pooled analysis of the diagnostic accuracy of F-18 fluoroestradiol (F-18 FES) positron emission tomography/computed tomography (PET/CT) assessing estrogen receptor expression of patients who have recurrent or metastatic breast cancer.
Methods: Two investigators and seven related experts (from the departments of nuclear medicine, hematological oncology, surgery, and evidence-based medicine) evaluated the effectiveness of F-18 FES PET/CT according to diagnostic accuracy and correlation with immunohistochemistry tests via systematic literature review, and safety according to test-related side effects. The present study was conducted in accordance with the Scottish Intercollegiate Guidelines (SIGN), and the Cochrane, and Preferred Reporting Items for Systematic Reviews and Meta Analyses guidelines. The SIGN tools were used for quality assessment.
Results: Of the 512 articles retrieved in the literature search, 8 were deemed to be eligible for inclusion. Results of the evaluation indicated that the F-18 FES PET/CT test was safe because patients who reported pain in the injection site in the analyzed articles are most likely to be caused by mechanical injury from needle injection not by administration of radioactive materials. Assessment of diagnostic accuracy based on data from seven studies revealed a pooled sensitivity and specificity of 0.86 and 0.85, respectively.
Conclusion: As such, the test was evaluated to be a safe and effective and, considering the anatomical site where only invasive tests are possible, the test was deemed to have high clinical utility.
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참고문헌 (32)
참고문헌 신청
Korean Breast Cancer Society / 2020 / Breast Cancer Facts & Figures 2020 / Korean Breast Cancer Society
National cancer information
Early Breast Cancer Trialists' Collaborative Group(EBCTCG) / 2011 / Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen : patient-level meta-analysis of randomised trials / Lancet 378(9793):771~784
Vollenweider-Zerargui L / 1986 / The predictive value of estrogen and progesterone receptors' concentrations on the clinical behavior of breast cancer in women. Clinical correlation on 547 patients / Cancer 57(6):1171~1180
Osborne CK / 1980 / The value of estrogen and progesterone receptors in the treatment of breast cancer / Cancer 46(12 Suppl):2884~2888
National cancer information
Early Breast Cancer Trialists' Collaborative Group(EBCTCG) / 2011 / Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen : patient-level meta-analysis of randomised trials / Lancet 378(9793):771~784
Vollenweider-Zerargui L / 1986 / The predictive value of estrogen and progesterone receptors' concentrations on the clinical behavior of breast cancer in women. Clinical correlation on 547 patients / Cancer 57(6):1171~1180
Osborne CK / 1980 / The value of estrogen and progesterone receptors in the treatment of breast cancer / Cancer 46(12 Suppl):2884~2888
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