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논문 기본 정보

자료유형
학술저널
저자정보
Cho Kee Hyun (Department of Pediatrics Kangwon National University Hospital Chuncheon Korea.) Yoon So Jin (Department of Pediatrics Yonsei University College of Medicine Seoul Korea.) Lim Joohee (Department of Pediatrics Yonsei University College of Medicine Seoul Korea.) Eun Hoseon (Department of Pediatrics Yonsei University College of Medicine Seoul Korea.) Park Min Soo (Department of Pediatrics Yonsei University College of Medicine Seoul Korea.) Park Kook In (Department of Pediatrics Yonsei University College of Medicine Seoul Korea.) Jo Heui Seung (Department of Pediatrics Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Ko) Lee Soon Min (Department of Pediatrics Yonsei University College of Medicine Seoul Korea.)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.36 No.47
발행연도
2021.12
수록면
1 - 9 (9page)
DOI
10.3346/jkms.2021.36.e320

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초록· 키워드

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Background: Macrosomia, as an infant with birth weight over 4 kg, can have several perinatal, and neonatal complications. This study aimed to estimate the incidence of macrosomia in Korea and to identify the growth and developmental outcomes and other neonatal complications. Methods: In total, 397,203 infants who were born in 2013 with birth weight ≥ 2.5 kg and who underwent infant health check-up between their 1st and 7th visit were included from the National Health Insurance Service database. The information was obtained by the International Classification of Diseases-10 codes or self-reported questionnaires in the National Health Screening Program. Results: The distribution of infants by birth weight was as follows: 384,181 (97%) infants in the 2.5?3.99 kg (reference) group, 12,016 (3%) infants in the 4.0?4.49 kg group, 772 (0.2%) infants in the 4.5?4.99 kg group, and 78 (0.02%) infants in the ≥ 5 kg group. Macrosomia showed significantly higher incidence of sepsis, male sex, and mothers with GDM and birth injury. There was a significant difference in weight, height, and head circumference according to age, birth weight group, and combination of age and birth weight, respectively (P < 0.001). The number of infants with the weight above the 90th percentile in macrosomia at each health check-up showed higher incidence than in reference group. The mean body mass index significantly differed among the groups, as 50.6 in infants with 2.5?3.99 kg of birth weight, 63.5 with 4.0?4.49 kg, 71.0 with 4.5?4.99 kg, and 73.1 with ≥ 5 kg. There was a significant difference in the incidence of poor developmental results between infants with macrosomia and the reference group at 24, 36 and 48 month of age. Conclusion: Macrosomia was significantly associated with the risk of sepsis, birth injury, obesity and developmental problem especially in a boy born from mothers with gestational diabetes mellitus. Careful monitoring and proper strategies for monitoring growth and development are needed.

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