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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.11
- 수록면
- 990 - 996 (7page)
- DOI
- 10.3349/ymj.2021.62.11.990
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초록· 키워드
오류제보하기
Purpose: Concerns have been consistently raised in regards to the considerable amount of contrast dye used during transcatheter aortic valve replacement (TAVR) in patients with renal insufficiency. In the present study, we introduced minimal contrast TAVR and compared its 30-day clinical outcomes with conventional TAVR.
Materials and Methods: We retrospectively investigated 369 patients who underwent TAVR between July 2011 and April 2020 in our institute. Among them, 93 patients with severe aortic stenosis and renal insufficiency (estimated glomerular filtration rate ≤50 mL/min/1.73 m2) were included and divided into a conventional TAVR group (n=56) and a minimal contrast TAVR group (n=37). In the minimal contrast TAVR group, the total amount of contrast was <10 mL during the entire TAVR procedure. Thirty-day major adverse clinical events (MACE), including death, stroke, implantation of permanent pacemaker, and initiation of hemodialysis, were investigated.
Results: The incidence of MACE was significantly lower in the minimal contrast TAVR group than the conventional TAVR group (16.2% vs. 42.9%, p=0.010). Death occurred in 9 patients (16.1%) in the conventional TAVR group and in 0 patients in the minimal contrast group (p=0.011). Hemodialysis was initiated in 2 patients (5.4%) in the minimal contrast TAVR group and in 7 patients (12.5%) in the conventional TAVR group (p=0.256). Multivariate regression analysis showed that the minimal contrast TAVR procedure was an independent predictor for reducing MACE (hazard ratio 0.208, 95% confidence interval: 0.080?0.541, p=0.001).
Conclusion: Minimal contrast TAVR is feasible and shows more favorable short-term clinical outcomes than conventional TAVR in patients with renal insufficiency.
목차
등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Franzone A / 2017 / Evolving indications for transcatheter aortic valve interventions / Curr Cardiol Rep 19:107
Reardon MJ / 2017 / Surgical or transcatheter aortic-valve replacement in intermediate-risk patients / N Engl J Med 376:1321~1331
Leon MB / 2016 / Transcatheter or surgical aortic-valve replacement in intermediate-risk patients / N Engl J Med 374:1609~1620
Popma JJ / 2019 / Transcatheter aortic-valve replacement with a self-expanding valve in low-risk patients / N Engl J Med 380:1706~1715
Mack MJ / 2019 / Transcatheter aortic-valve replacement with a balloon-expandable valve in low-risk patients / N Engl J Med 380:1695~1705
Reardon MJ / 2017 / Surgical or transcatheter aortic-valve replacement in intermediate-risk patients / N Engl J Med 376:1321~1331
Leon MB / 2016 / Transcatheter or surgical aortic-valve replacement in intermediate-risk patients / N Engl J Med 374:1609~1620
Popma JJ / 2019 / Transcatheter aortic-valve replacement with a self-expanding valve in low-risk patients / N Engl J Med 380:1706~1715
Mack MJ / 2019 / Transcatheter aortic-valve replacement with a balloon-expandable valve in low-risk patients / N Engl J Med 380:1695~1705
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