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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.6
- 수록면
- 294 - 298 (5page)
- DOI
- https://doi.org/10.3904/kjm.2019.94.3.294
이용수
초록· 키워드
오류제보하기
Bedaquiline and delamanid were recently approved for the treatment of multidrug-resistant tuberculosis (MDR-TB) in Korea. A treatment duration of 24 weeks was established based on phase 2 clinical trial data, although the combined use of these two drugs is typically not recommended because it may exaggerate QT prolongation. Here, we present a case of prolonged treatment (48 weeks) with a combination of bedaquiline and delamanid for pulmonary MDR-TB. The patient had previously been diagnosed with extensively drug-resistant TB but had been left untreated for the past 9 years due to a shortage of effective drugs. A combination of bedaquiline and delamanid successfully treated MDR-TB, highlighting the potential efficacy of these drugs for patients with drug-resistant TB infections.
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참고문헌 (10)
참고문헌 신청
Korea Centers for Disease Control / 2018 / Tuberculosis notification status in Korea in 2017 / Public Health Weekly Report 11:401~406
Caminero JA / 2017 / Proposal for a standardised treatment regimen to manage pre-and extensively drug-resistant tuberculosis cases / Eur Respir J 50:1700648
World Health Organization / World Health Organization. WHO treatment guidelines for drug-resistant tuberculosis, 2016 update [Internet]. Geneva(CH) : World Health Organization, c2016 [cited 2018 May 29]. Available from
Korea Centers for Disease Control and Prevention / 2017 / Multidrug-resistant tuberculosis status and performance of the Healthcare Review Committee for new drugs for MDR-TB in the Republic of Korea / Public Health Weekly Report 10:1362~1368
Lee YS / 2017 / Performance of the GenoType MTBDRsl assay for the detection second-line anti-tuberculosis drug resistance / J Infect Chemother 23:820~825
Caminero JA / 2017 / Proposal for a standardised treatment regimen to manage pre-and extensively drug-resistant tuberculosis cases / Eur Respir J 50:1700648
World Health Organization / World Health Organization. WHO treatment guidelines for drug-resistant tuberculosis, 2016 update [Internet]. Geneva(CH) : World Health Organization, c2016 [cited 2018 May 29]. Available from
Korea Centers for Disease Control and Prevention / 2017 / Multidrug-resistant tuberculosis status and performance of the Healthcare Review Committee for new drugs for MDR-TB in the Republic of Korea / Public Health Weekly Report 10:1362~1368
Lee YS / 2017 / Performance of the GenoType MTBDRsl assay for the detection second-line anti-tuberculosis drug resistance / J Infect Chemother 23:820~825
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