지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.8
- 수록면
- 343 - 352 (10page)
- DOI
- https://doi.org/10.3904/kjm.2019.94.4.343
이용수
초록· 키워드
오류제보하기
Mycobacterium abscessus is the second most important pathogen in pulmonary disease caused by nontuberculous mycobacteria (NTM), following Mycobacterium avium. Mycobacterium abscessus is classified into three subspecies: M. abscessus subsp. abscessus, M. abscessus subsp. massiliense, and M. abscessus subsp. bolletii. Mycobacterium abscessus is the most difficult to treat NTM due to its resistance to many antibiotics. Treatment should include an initial regimen of 2-3 injectable and oral antibiotics for several weeks or months, followed by inhaled amikacin and 1-3 oral antibiotics, depending on the subspecies and drug susceptibility patterns, including macrolide susceptibility. The continuation phase should be continued for a minimum of 12 months after culture conversion. Suitable injectable antibiotics include amikacin, imipenem, cefoxitin, and tigecycline, while oral antibiotics include macrolides (azithromycin or clarithromycin), clofazimine, linezolid, and moxifloxacin. Surgery can be a useful adjunctive therapy for some patients with refractory disease. However, the overall treatment prognosis is still unsatisfactory. Therefore, novel and more effective interventions are required for the treatment of M. abscessus pulmonary disease.
목차
등록된 정보가 없습니다.
참고문헌 (64)
참고문헌 신청
Griffith DE / 2007 / An official ATS/IDSA statement : diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases / Am J Respir Crit Care Med 175:367~416
Honda JR / 2018 / Global environmental nontuberculous mycobacteria and their contemporaneous man-made and natural niches / Front Microbiol 9:2029
Jeon D / 2019 / Infection source and epidemiology of nontuberculous mycobacterial lung disease / Tuberc Respir Dis(Seoul) 82:94~101
Lee H / 2019 / Epidemiology of nontuberculous mycobacterial infection, South Korea, 2007-2016 / Emerg Infect Dis 25:569~572
Yoon HJ / 2017 / Nontuberculosis mycobacterial infections at a specialized tuberculosis treatment centre in the Republic of Korea / BMC Infect Dis 17:432
Honda JR / 2018 / Global environmental nontuberculous mycobacteria and their contemporaneous man-made and natural niches / Front Microbiol 9:2029
Jeon D / 2019 / Infection source and epidemiology of nontuberculous mycobacterial lung disease / Tuberc Respir Dis(Seoul) 82:94~101
Lee H / 2019 / Epidemiology of nontuberculous mycobacterial infection, South Korea, 2007-2016 / Emerg Infect Dis 25:569~572
Yoon HJ / 2017 / Nontuberculosis mycobacterial infections at a specialized tuberculosis treatment centre in the Republic of Korea / BMC Infect Dis 17:432
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