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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.6
- 수록면
- 181 - 187 (7page)
- DOI
- https://doi.org/10.3904/kjm.2020.95.3.181
이용수
초록· 키워드
오류제보하기
Fecal microbiota transplantation (FMT), which has been established as the standard treatment for recurrent Clostroides difficile infection, may also play a role in the management of other diseases associated with dysbiosis of the gut microbiota. To ensure efficacy and safety of FMT, an appropriate donor screening process is required. The main purpose of donor screening is to check for infectious diseases that could be transmitted to the recipient. The screening process involves a medical history questionnaire, and blood and stool testing. Several randomized clinical trials and large case series on FMT reported no, or few, adverse events related to infection by following this donor screening process. However, there is still concern over the transmission of antibiotic-resistant bacteria. In addition, a low donor acceptance rate due to rigorous screening makes donor recruitment difficult, and also imposes a significant cost burden. A consensus on the most crucial elements of donor screening is needed for wide application of FMT.
목차
등록된 정보가 없습니다.
참고문헌 (38)
참고문헌 신청
Kassam Z / 2013 / Fecal microbiota transplantation for Clostridium difficile infection : systematic review and meta-analysis / Am J Gastroenterol 108:500~508
van Nood E / 2013 / Duodenal infusion of donor feces for recurrent Clostridium difficile / N Engl J Med 368:407~415
McDonald LC / 2018 / Clinical practice guidelines for Clostridium difficile infection in adults and children : 2017 update by the Infectious Diseases Society of America(IDSA)and Society for Healthcare Epidemiology of America(SHEA) / Clin Infect Dis 66:987~994
Rossen NG / 2015 / Findings from a randomized controlled trial of fecal transplantation for patients with ulcerative colitis / Gastroenterology 149:110~118
Moayyedi P / 2015 / Fecal microbiota transplantation induces remission in patients with active ulcerative colitis in a randomized controlled trial / Gastroenterology 149:102~109
van Nood E / 2013 / Duodenal infusion of donor feces for recurrent Clostridium difficile / N Engl J Med 368:407~415
McDonald LC / 2018 / Clinical practice guidelines for Clostridium difficile infection in adults and children : 2017 update by the Infectious Diseases Society of America(IDSA)and Society for Healthcare Epidemiology of America(SHEA) / Clin Infect Dis 66:987~994
Rossen NG / 2015 / Findings from a randomized controlled trial of fecal transplantation for patients with ulcerative colitis / Gastroenterology 149:110~118
Moayyedi P / 2015 / Fecal microbiota transplantation induces remission in patients with active ulcerative colitis in a randomized controlled trial / Gastroenterology 149:102~109
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