지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제5권 제4호
- 발행연도
- 2017.7
- 수록면
- 211 - 216 (6page)
- DOI
- https://doi.org/10.4168/aard.2017.5.4.211
이용수
초록· 키워드
오류제보하기
Purpose: Chronic spontaneous urticaria (CSU) in children is a common skin disorder, but its clinical course varies. We investigated the clinical course and associated factors for CSU treatment in children.
Methods: A total of 107 children, diagnosed with CSU from 2001 to 2016 in Dong-A University Hospital, who had been followed up for more than 6 months after treatment, were enrolled. The laboratory findings, and clinical aspects and courses were retrospectively investigated by a medical record review. We divided the 152 patients into 3 groups according to the treatment modalities: group 1, 1 antihistamine; group 2, more than 2 kinds of antihistamines; and group 3, antihistamines plus leukotriene receptor antagonist.
Results: The mean age of patients in group 3 was 3.4 years (range, 2.6?4.2 years), which was significantly lower than those at the other 2 group patients (P=0.01). The urticaria activity score (UAS) of group 3 (6.1 [5.7?6.6]) was significantly higher compared to those of the other 2 groups (P=0.01). The improvement rate of the condition in children with positive specific immunoglobulin E (sIgE) reactivity to food or inhalant allergens was significantly lower than that of children with negative sIgE reactivity (P=0.01). Sex, age, history of allergic diseases, disease duration, UAS, previous treatment, and treatment modality were not correlated with the symptom improvement rate.
Conclusion: Younger children and those with higher UAS needed more medication to ensure the improvement in symptoms. Moreover, it took more time for the improvement in symptoms in children who were sensitized to food or inhalant allergens.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Zuberbier T / 2014 / The EAACI/GA(2) LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update / Allergy 69:868~887
유진호 / 2014 / 소아 만성 두드러기 / Allergy Asthma & Respiratory Diseases 2(4):236~242
Marrouche N / 2012 / Childhood urticaria / Curr Opin Allergy Clin Immunol 12:485~490
Leech S / 2011 / The RCPCH care pathway for children with urticaria, angio-oedema or mastocytosis: an evidence and consensus based national approach / Arch Dis Child 96(Suppl 2):i34~i37
Kaplan AP / 2002 / Clinical practice. Chronic urticaria and angioedema / N Engl J Med 346:175~179
유진호 / 2014 / 소아 만성 두드러기 / Allergy Asthma & Respiratory Diseases 2(4):236~242
Marrouche N / 2012 / Childhood urticaria / Curr Opin Allergy Clin Immunol 12:485~490
Leech S / 2011 / The RCPCH care pathway for children with urticaria, angio-oedema or mastocytosis: an evidence and consensus based national approach / Arch Dis Child 96(Suppl 2):i34~i37
Kaplan AP / 2002 / Clinical practice. Chronic urticaria and angioedema / N Engl J Med 346:175~179
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