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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.6
- 수록면
- 510 - 514 (5page)
- DOI
- 10.9799/ksfan.2017.30.3.510
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초록· 키워드
오류제보하기
Plantago asiatica L., observed frequently in East Asia, is a known herb used in traditional medical remedies several studies report that P. asiatica L has anti-inflammatory and antioxidant effects. To determine the production of cytokines (IL-2, IFN-γ, and TNF-α) induced by lipopolysaccharide (LPS) and non-LPS-stimulated macrophages, an ELISA assay was conducted using cytokine kits. Mice splenocytes were cultured for 48 h with various concentrations of P. asiatica L. (5, 10, 50, 100, 250, 500, and 1,000 μg/mL) or with mitogens (ConA or LPS). P. asiatica L. increased the proliferation of mice splenocytes, especially under the condition of its concentration ranging from 250 to 1,000 μg/mL. In addition, Plantago asiatica L. notably induced cytokine production of (IL-2, IFN-γ, and TNF-α) at its concentration of 250~500 μg/mL. These results suggest that supplementation with P. asiatica L. water extracts may play a potential role in enhancing immune function by mediating splenocyte proliferation and cytokine production through its anti-inflammatory activit.
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등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Anderson JW / 1999 / Effects of psyllium on glucose and serum lipid responses in men eith type 2 diabetes and hypercholesterolmia / Am J Clin Nutr 7:1433~1438
Barnes PJ / 1995 / Nitric oxide and asthmatic inflammation / Immunology Today 16:128~130
Bhol KC Rojas AI / 2000 / Presence of interleukin 10 in the serum and blister fluid of patients with Pemphigus vulgaris and pemphigoid / Cytokine 12:76~83
Chang IM / 1998 / Liver-protective activites of aucubin derved from traditional oriental medicine / Res Commun Mol Pathol Phamacog 11:57~60
Davidson MH / 1998 / Long-term effects of consuming foods containing psyllium seed husk on serum lipids in subjects with hypercholesterolemia / The American Journal of Clinical Nutrition 67:367~376
Barnes PJ / 1995 / Nitric oxide and asthmatic inflammation / Immunology Today 16:128~130
Bhol KC Rojas AI / 2000 / Presence of interleukin 10 in the serum and blister fluid of patients with Pemphigus vulgaris and pemphigoid / Cytokine 12:76~83
Chang IM / 1998 / Liver-protective activites of aucubin derved from traditional oriental medicine / Res Commun Mol Pathol Phamacog 11:57~60
Davidson MH / 1998 / Long-term effects of consuming foods containing psyllium seed husk on serum lipids in subjects with hypercholesterolemia / The American Journal of Clinical Nutrition 67:367~376
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