Risk Stratification of T1 Colorectal Cancer Metastasis to Lymph Nodes: Current Status and Perspective

Ichimasa Katsuro; Kudo Shin-ei; Miyachi Hideyuki; Kouyama Yuta; Misawa Masashi; Mori Yuichi

doi:10.5009/gnl20224

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자료유형: 학술저널

저자정보: Ichimasa Katsuro (Digestive Disease Center Showa University Northern Yokohama Hospital Yokohama Japan) Kudo Shin-ei (Digestive Disease Center Showa University Northern Yokohama Hospital Yokohama Japan) Miyachi Hideyuki (Digestive Disease Center Showa University Northern Yokohama Hospital Yokohama Japan) Kouyama Yuta (Digestive Disease Center Showa University Northern Yokohama Hospital Yokohama Japan) Misawa Masashi (Digestive Disease Center Showa University Northern Yokohama Hospital Yokohama Japan) Mori Yuichi (Digestive Disease Center Showa University Northern Yokohama Hospital Yokohama JapanClinical Effecti)

저널정보: 거트앤리버 발행위원회 Gut and Liver Gut and Liver 제15권 제6호

발행연도: 2021.11

수록면: 818 - 826 (9page)

DOI: 10.5009/gnl20224

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With the widely spreading population-based screening programs for colorectal cancer and recent improvements in endoscopic diagnosis, the number of endoscopic resections in subjects with T1 colorectal cancer has been increasing. Some reports suggest that endoscopic resection prior to surgical resection of T1 colorectal cancer has no adverse effect on prognosis and contributes to this tendency. The decision on the need for surgical resection as an additional treatment after endoscopic resection of T1 colorectal cancer should be made according to the metastasis risk to lymph nodes based on histopathological findings. Because lymph node metastasis occurs in approximately 10% of patients with T1 colorectal cancer according to current international guidelines, the remaining 90% of patients may be at an increased risk of surgical resection and associated postoperative mortality, with no clinical benefit derived from unnecessary surgical resection. Although a more accurate prediction system for lymph node metastasis is needed to solve this problem, risk stratification for lymph node metastasis remains controversial. In this review, we focus on the current status of risk stratification of T1 colorectal cancer metastasis to lymph nodes and outline future perspectives.

#Lymph node metastasis #Treatment strategy #T1 colorectal cancer #Endoscopic resection #Surgical resection

참고문헌 (81)

참고문헌 신청

International Agency for Research on Cancer (IARC) / Cancer today

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