지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Objectives: The goal of this study was to identify chronic conditions and multimorbidity patterns in patients with coronavirus disease 2019 (COVID-19) and to examine their associations with pneumonia and death. Methods: This cross-sectional study analyzed the official data of COVID-19 patients in Mexico through May 18, 2020 (released by the Secretaria de Salud de Mexico). Adjusted logistic regression models were applied to assess the associations of comorbidities with pneumonia and death. The marginal effects were estimated, and the probability of pneumonia or death according to the number of comorbidities was graphed for each year of age. Results: Of the 51 053 COVID-19 patients enrolled in the final analysis, 27 667 (54.2%) had no chronic conditions, while 13 652 (26.7%), 6518 (12.8%) and 3216 (6.3%) were reported to have 1, 2, and 3 or more simultaneous conditions, respectively. Overall, a significant incremental gradient was observed for the association between multimorbidity and pneumonia (p<0.001); for 2 chronic conditions, the adjusted odds ratio (aOR) was 2.07 (95% confidence interval [CI], 1.95 to 2.20), and for ≥3 conditions, the aOR was 2.40 (95% CI, 2.22 to 2.60). A significant incremental gradient was also found for the relationship between multimorbidity and death (p<0.001); an aOR of 2.51 (95% CI, 2.30 to 2.73) was found for 2 chronic conditions and an aOR of 3.49 (95% CI, 3.15 to 3.86) for ≥3 conditions. Conclusions: Underlying chronic conditions and multimorbidity are associated with pneumonia and death in Mexican COVID-19 patients. Future investigation is necessary to clarify the pathophysiological processes behind this association, given the high burden of chronic diseases in various countries, including Mexico. Key words: Comorbidity, COVID-19, Multimorbidity, Severe acute respiratory syndrome coronavirus
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참고문헌 (35)
참고문헌 신청
Coronavirus Resource Center, Johns Hopkins University / Maps & trends
Wang D / 2020 / Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China / JAMA 323(11):1061~1069
Huang C / 2020 / Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China / Lancet 395(10223):497~506
Fang L / 2020 / Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection / Lancet Respir Med 8(4):e21
Varga Z / 2020 / Endothelial cell infection and endotheliitis in COVID-19 / Lancet 395(10234):1417~1418
Wang D / 2020 / Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China / JAMA 323(11):1061~1069
Huang C / 2020 / Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China / Lancet 395(10223):497~506
Fang L / 2020 / Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection / Lancet Respir Med 8(4):e21
Varga Z / 2020 / Endothelial cell infection and endotheliitis in COVID-19 / Lancet 395(10234):1417~1418
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