지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 충북대학교 동물의학연구소 Journal of Biomedical and Translational Research Journal of Biomedical and Translational Research 제19권 제4호
- 발행연도
- 2018.12
- 수록면
- 125 - 129 (5page)
이용수
초록· 키워드
오류제보하기
Dopaminergic neurons are one of the major neuronal components in the brain. Mesencephalon dopamine (DA) neurogenesis takes place in the ventricular zone of the floor plate, when DA progenitors divide to generate postmitotic cells. These cells migrate through the intermediate zone while they differentiate and become DA neurons on reaching the mantle zone. However, neurogenesis and neuronal migration on dopaminergic neurons remain largely unexplored in the mesencephalon development. This study presents neurogenesis and neuronal migration patterns of dopaminergic neurons during mesencephalic development of the mouse. Neurons from embryonic day (E) 10?14 were labelled by a single injection of 5-bromodeoxyuridine and immunohistochemistry was performed. The neurogenesis occurred mainly at the E10 and E11, which was uniformly distributed in the mesencephalic region, but neurons after E13 were observed only in the dorsal mesencephalon. At the postnatal day 0 (P0), E10 generated neurons were spread out uniformly in the whole mesencephalon whereas E11-originated neurons were clearly depleted in the red nucleus region. DA neurons mainly originated in the ventromedial mesencephalon at the early embryonic stage especially E10 to E11. DA neurons after E12 were only observed in the ventral mesencephalon. At E17, E10 labelled neurons were only observed in the substantia nigra (SN) region. Our study demonstrated that major neurogenesis occurred at E10 and E11. However, neuronal migration continued until neonatal period during mesencephalic development.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Altman J / 1981 / Development of the brain stem in the rat. V. Thymidine-radiographic study of the time of origin of neurons in the midbrain tegmentum / J Comp Neurol 198:677~716
Arenas E / 2015 / How to make a midbrain dopaminergic neuron / Development 142:1918~1936
Corbin JG / 2001 / Telencephalic cells take a tangent: non-radial migration in the mammalian forebrain / Nat Neurosci 4:1177~1182
Hatten ME / 2002 / New directions in neuronal migration / Science 297:1660~1663
Marin O / 2001 / A long, remarkable journey: tangential migration in the telencephalon / Nat Rev Neurosci 2:780~790
Arenas E / 2015 / How to make a midbrain dopaminergic neuron / Development 142:1918~1936
Corbin JG / 2001 / Telencephalic cells take a tangent: non-radial migration in the mammalian forebrain / Nat Neurosci 4:1177~1182
Hatten ME / 2002 / New directions in neuronal migration / Science 297:1660~1663
Marin O / 2001 / A long, remarkable journey: tangential migration in the telencephalon / Nat Rev Neurosci 2:780~790
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Neurogenesis of dopaminergic and GABAergic neurons during mesencephalon development in mice
한국실험동물학회 학술발표대회 논문집
2019 .01
-
Dopaminergic neuronal development in the embryonic mesencephalon of mouse
Korean Journal of Veterinary Research(대한수의학회지)
2020 .12
-
Dopaminergic neuronal development in the embryonic mesencephalon of Mice
한국실험동물학회 학술발표대회 논문집
2020 .02
-
GABAergic neuronal development in the embryonic mesencephalon of mice
Korean Journal of Veterinary Research(대한수의학회지)
2020 .02
-
Abnormal neuronal migration of Pitx3-deficient aphakia mouse (ak/ak) in the embryonic mesencephalon
한국실험동물학회 학술발표대회 논문집
2022 .01
-
Distinct cell populations of ventral tegmental area process motivated behavior
The Korean Journal of Physiology & Pharmacology
2022 .09
-
Dopamine D1-like receptor regulates GAD-67 expression following degeneration of dopaminergic neuron
한국실험동물학회 학술발표대회 논문집
2017 .02
-
From Neurons to Social Beings: Short Review of the Mirror Neuron System Research and Its Socio-Psychological and Psychiatric Implications
Clinical Psychopharmacology and Neuroscience
2018 .01
-
Comparison of electrophysiological properties of two types of pre-sympathetic neurons intermingled in the hypothalamic paraventricular nucleus
Journal of Veterinary Science
2018 .07
-
A functional neuron maturation device provides convenient application on microelectrode array for neural network measurement
생체재료학회지
2023 .03
-
Past, Present, and Future in the Study of Neural Control of the Lower Urinary Tract
International Neurourology Journal
2020 .01
-
미토콘드리아 기능을 통해 내인성 글루탐산이 신경세포 생존에 미치는 영향
의생명과학
2018 .01
-
Protective effect of the aerial parts of Silybum marianum against amyloid β protein (25-35)-induced neuronal death in cultured neurons
Journal of Biomedical and Translational Research
2016 .12
-
Role of neuron and non-neuronal cell communication in persistent orofacial pain
Journal of dental anesthesia and pain medicine
2019 .01
-
Isolation and culture of porcine primary fetal progenitors and neurons from the developing dorsal telencephalon
Journal of Veterinary Science
2019 .03
-
Asiatic Acid Protects Dopaminergic Neurons from Neuroinflammation by Suppressing Mitochondrial ROS Production
Biomolecules & Therapeutics(구 응용약물학회지)
2019 .01
-
Motor Neuron Disease Presenting With Acute Respiratory Failure: A Case Study
Annals of Rehabilitation Medicine
2017 .01
-
IGF-1 protects neurons in the cortex and subventricular zone in a periventricular leucomalacia model
대한체질인류학회 학술대회 연제 초록
2021 .05
-
Evaluation of PFAS on neuronal activity and survival in cortical neurons
환경독성보건학회 심포지엄 및 학술대회
2022 .10
-
Cellular Response of Ventricular-Subventricular Neural Progenitor/Stem Cells to Neonatal Hypoxic-Ischemic Brain Injury and Their Enhanced Neurogenesis
Yonsei Medical Journal
2020 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0