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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.8
- 수록면
- 176 - 187 (12page)
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초록· 키워드
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Objectives: This study aimed to evaluate the chemical and biological properties of fast-set white mineral trioxide aggregate (FS WMTA), which was WMTA combined with calcium chloride dihydrate (CaCl2·2H2O), compared to that of WMTA.
Materials and Methods: Surface morphology, elemental, and phase analysis were examined using scanning electron microscope (SEM), energy dispersive X-ray microanalysis (EDX), and X-ray diffraction (XRD), respectively. The cytotoxicity and cell attachment properties were evaluated on human periodontal ligament fibroblasts (HPLFs) using methyl-thiazol-diphenyltetrazolium (MTT) assay and under SEM after 24 and 72 hours, respectively.
Results: Results showed that the addition of CaCl2·2H2O to WMTA affected the surface morphology and chemical composition. Although FS WMTA exhibited a non-cytotoxic profile, the cell viability values of this combination were lesser than WMTA, and the difference was significant in 7 out of 10 concentrations at the 2 time intervals (p < 0.05). HPLFs adhered over the surface of WMTA and at the interface, after 24 hours of incubation. After 72 hours, there were increased numbers of HPLFs with prominent cytoplasmic processes. Similar findings were observed with FS WMTA, but the cells were not as confluent as with WMTA.
Conclusions: The addition of CaCl2·2H2O to WMTA affected its chemical properties. The favorable biological profile of FS WMTA towards HPLFs may have a potential impact on its clinical application for repair of perforation defects.
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참고문헌 (52)
참고문헌 신청
Torabinejad M / 1993 / Pitt Ford TR. Sealing ability of a mineral trioxide aggregate when used as a root end filling material / J Endod 19:591~595
Al-Rabeah E / 2006 / Human alveolar bone cells interact with ProRoot and tooth-colored MTA / J Endod 32:872~875
Nair PN / 2008 / Histological, ultrastructural and quantitative investigations on the response of healthy human pulps to experimental capping with mineral trioxide aggregate: a randomized controlled trial / Int Endod J 41:128~150
Torabinejad M / 2010 / Mineral trioxide aggregate: a comprehensive literature review--part II: leakage and biocompatibility investigations / J Endod 36:190~202
Hakki SS / 2012 / Periodontal ligament fibroblast response to root perforations restored with different materials: a laboratory study / Int Endod J 45:240~248
Al-Rabeah E / 2006 / Human alveolar bone cells interact with ProRoot and tooth-colored MTA / J Endod 32:872~875
Nair PN / 2008 / Histological, ultrastructural and quantitative investigations on the response of healthy human pulps to experimental capping with mineral trioxide aggregate: a randomized controlled trial / Int Endod J 41:128~150
Torabinejad M / 2010 / Mineral trioxide aggregate: a comprehensive literature review--part II: leakage and biocompatibility investigations / J Endod 36:190~202
Hakki SS / 2012 / Periodontal ligament fibroblast response to root perforations restored with different materials: a laboratory study / Int Endod J 45:240~248
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