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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.11
- 수록면
- 232 - 239 (8page)
- DOI
- https://doi.org/10.5469/neuroint.2021.00227
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초록· 키워드
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Purpose: The treatment of aneurysms with characteristics such as complex morphology, fusiform, blister-like, wide neck, or large size has been revolutionized with the introduction of flow diverters. Though flow diverters have several advantages over coiling, they also have certain important disadvantages such as the lack of immediate protection against rupture, the risk of ischemic stroke, the need for antiplatelet therapy, and long latency for complete effect. The Derivo Embolization Device (DED) is a second-generation self-expanding device that is claimed to be less thrombogenic than conventional devices. We retrospectively evaluated the periprocedural safety and risks associated with the DED across 5 centers in India.
Materials and Methods: This is a multicentric, retrospective, observational study of DED, conducted at 5 high volume endovascular therapy centers in India from May 2018 to June 2020. Periprocedural demographic, clinical, and angiographic data were collected from a retrospective review of patient charts.
Results: A total of 96 patients, including 56 (58.3%) females, aged between 16?80 years (60±12.7 years) harboring 106 aneurysms were studied. Seven (7.3%) were noted to harbor multiple aneurysms: 6 had 3 aneurysms each, while 1 patient had 5 aneurysms. The following aneurysm characteristics were noted: average size, 9.8±8.2 mm; average neck size, 6.9±8.5 mm; wide-necked (>4 mm), 63 (59.4%); giant (>25 mm), 8 (7.5%); and anterior circulation location, 98 (92.5%). Eighteen (17%) of these were ruptured. Additional balloon angioplasty was performed in 5 (5.2%) patients. Intraprocedural problems were encountered in 3 (3.1%), of which only 1 had clinical implications, the device fish-mouthing with stent thrombosis resulting in a malignant middle cerebral artery territory infarction. The modified Rankin scale at 3 months was worse in 1 patient.
Conclusion: DED is a newer generation flow diverter stent with a low periprocedural complication rate.
목차
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참고문헌 (28)
참고문헌 신청
Molyneux AJ / 2005 / International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion / Lancet 366:809~817
Piotin M / 2007 / Intracranial aneurysms : treatment with bare platinum coils--aneurysm packing, complex coils, and angiographic recurrence / Radiology 243:500~508
Lylyk P / 2009 / Curative endovascular reconstruction of cerebral aneurysms with the pipeline embolization device : the Buenos Aires experience / Neurosurgery 64:632~642
Nelson PK / 2011 / The pipeline embolization device for the intracranial treatment of aneurysms trial / AJNR Am J Neuroradiol 32:34~40
Becske T / 2013 / Pipeline for uncoilable or failed aneurysms : results from a multicenter clinical trial / Radiology 267:858~868
Piotin M / 2007 / Intracranial aneurysms : treatment with bare platinum coils--aneurysm packing, complex coils, and angiographic recurrence / Radiology 243:500~508
Lylyk P / 2009 / Curative endovascular reconstruction of cerebral aneurysms with the pipeline embolization device : the Buenos Aires experience / Neurosurgery 64:632~642
Nelson PK / 2011 / The pipeline embolization device for the intracranial treatment of aneurysms trial / AJNR Am J Neuroradiol 32:34~40
Becske T / 2013 / Pipeline for uncoilable or failed aneurysms : results from a multicenter clinical trial / Radiology 267:858~868
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