지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.6
- 수록면
- 46 - 52 (7page)
- DOI
- https://doi.org/10.12997/jla.2017.6.1.46
이용수
초록· 키워드
오류제보하기
We investigated the importance of comprehensive physiologic assessment about culprit vessel in STEMI in estimating long-term clinical outcomes after complete revascularization. Comprehensive physiologic assessment provides additional information about microvascular function in coronary artery disease. This assessment includes three indices, fractional flow reserve (FFR), index of microcirculatory resistance (IMR) and coronary flow reserve (CFR). We have performed the comprehensive physiologic assessment in culprit vessels after successful primary PCI in STEMI patients. Both cases were thrombotic total occlusion in mid right coronary artery with inferior wall STEMI, successfully revascularized with stent implantation after thrombus suction. However, in post PCI physiologic assessment, one case showed overt microvascular damage. CFR was 1.1, and IMR was 75U, which was defined as a combined criterion of low CFR (<2.0) and high IMR (≥25U) in culprit vessel, but the other case showed 2.2 in CFR and 24U in IMR, which suggested no overt microvascular damage. Moreover, we can validate these findings by cardiac MR after primary PCI. Previous studies presented that the presence of overt microvascular damage was significantly associated with worse clinical outcome in patients with coronary artery disease.
We suggest that comprehensive physiologic evaluation provides important information about the degree of microvascular damage and long-term clinical outcomes after complete revascularization in culprit vessel in STEMI.
목차
등록된 정보가 없습니다.
참고문헌 (9)
참고문헌 신청
Fearon WF / 2013 / Prognostic value of the index of microcirculatory resistance measured after primary percutaneous coronary intervention / Circulation 127:2436~2441
McGeoch R / 2010 / The index of microcirculatory resistance measured acutely predicts the extent and severity of myocardial infarction in patients with ST-segment elevation myocardial infarction / JACC Cardiovasc Interv 3:715~722
van de Hoef TP / 2013 / Impact of coronary microvascular function on long-term cardiac mortality in patients with acute ST-segment-elevation myocardial infarction / Circ Cardiovasc Interv 6:207~215
Lee JM / 2016 / Coronary flow reserve and microcirculatory resistance in patients with intermediate coronary stenosis / J Am Coll Cardiol 67:1158~1169
Lim HS / 2009 / Usefulness of the index of microcirculatory resistance for invasively assessing myocardial viability immediately after primary angioplasty for anterior myocardial infarction / Eur Heart J 30:2854~2860
McGeoch R / 2010 / The index of microcirculatory resistance measured acutely predicts the extent and severity of myocardial infarction in patients with ST-segment elevation myocardial infarction / JACC Cardiovasc Interv 3:715~722
van de Hoef TP / 2013 / Impact of coronary microvascular function on long-term cardiac mortality in patients with acute ST-segment-elevation myocardial infarction / Circ Cardiovasc Interv 6:207~215
Lee JM / 2016 / Coronary flow reserve and microcirculatory resistance in patients with intermediate coronary stenosis / J Am Coll Cardiol 67:1158~1169
Lim HS / 2009 / Usefulness of the index of microcirculatory resistance for invasively assessing myocardial viability immediately after primary angioplasty for anterior myocardial infarction / Eur Heart J 30:2854~2860
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