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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.12
- 수록면
- 84 - 88 (5page)
- DOI
- https://doi.org/10.12997/jla.2017.6.2.84
이용수
초록· 키워드
오류제보하기
Objectives: Overt hypothyroidism has been associated with abnormalities of lipid metabolism; however conflicting resultsregarding the degree of lipid changes in subclinical hypothyroidism (SCH) have been reported. The aim of this study wasto assess differences in lipid profile parameters between people with and without SCH in Korean population.
Methods: Serum lipid parameters of 37 patients with SCH and 44 euthyroid control subjects were evaluated in a retrospectivecross-sectional study.
Results: The mean serum triglycerides (TG) level was significantly higher in patients with SCH than in controls (p<0.05).
The mean serum high-density lipoprotein cholesterol (HDL-C) level was significantly lower in patients with SCH than incontrols (p<0.05). When adjusted by age, the odds ratio for the association of HDL-C with SCH was significant at 0.893(95% confidence interval 0.809-0.986) compared with that of the euthyroid controls. No association with SCH was foundwith total cholesterol level, low-density lipoprotein cholesterol level or serum thyroid-stimulating hormone level. In addition,the lipid profile did not differ significantly between premenopausal and postmenopausal women.
Conclusions: We found variations of lipid profiles in patients with SCH, characterized by a significantly lower HDL-C level.
(J Lipid Atheroscler 2017 December;6(2):84-88)
목차
등록된 정보가 없습니다.
참고문헌 (11)
참고문헌 신청
Duntas LH / 2002 / Thyroid disease and lipids / Thyroid 12:287~293
Desai JP / 2015 / A study of correlation of serum lipid profile in patients with hypothyroidism / Int J Med Sci Public Health 4:1108~1112
Milionis HJ / 2005 / Thyroid substitution therapy induces high-density lipoprotein-associated plateletactivating factor-acetylhydrolase in patients with subclinical hypothyroidism: a potential antiatherogenic effect / Thyroid 15:455~460
Toruner F / 2008 / Risk factors for cardiovascular disease in patients with subclinical hypothyroidism / Adv Ther 25:430~437
Erdem TY / 2008 / Plasma viscosity, an early cardiovascular risk factor in women with subclinical hypothyroidism / Clin Hemorheol Microcirc 38:219~225
Desai JP / 2015 / A study of correlation of serum lipid profile in patients with hypothyroidism / Int J Med Sci Public Health 4:1108~1112
Milionis HJ / 2005 / Thyroid substitution therapy induces high-density lipoprotein-associated plateletactivating factor-acetylhydrolase in patients with subclinical hypothyroidism: a potential antiatherogenic effect / Thyroid 15:455~460
Toruner F / 2008 / Risk factors for cardiovascular disease in patients with subclinical hypothyroidism / Adv Ther 25:430~437
Erdem TY / 2008 / Plasma viscosity, an early cardiovascular risk factor in women with subclinical hypothyroidism / Clin Hemorheol Microcirc 38:219~225
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