지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.9
- 수록면
- 146 - 152 (7page)
- DOI
- 10.25289/ML.2021.10.3.146
이용수
초록· 키워드
오류제보하기
Background and Objectives Although lasers have been widely applied in tissue treatment, the light penetration depth in tissues is limited by the tissue turbidity and affected by its absorption and scattering characteristics. This study investigated the effect of using an optical clearing agent (OCA) on tissue to improve the therapeutic effect of 1064 nm wavelength laser light by reducing the heat generated on the skin surface and increasing the penetration depth.
Materials and Methods A diode laser (λ = 1064 nm) was applied to a porcine specimen with and without OCA to investigate the penetration depth of the laser light and temperature distribution. A numerical simulation using the finite element method was performed to investigate the temperature distribution of the specimen compared to ex-vivo experiments using a thermocouple and double-integrating sphere to measure the temperature profile and optical properties of the tissue, respectively.
Results Simulation results showed a decrease in tissue surface temperature with increased penetration depth when the OCA was applied. Furthermore, both absorption and scattering coefficients decreased with the application of OCA. In ex-vivo experiments, temperatures decreased for the tissue surface and the fat layer with the OCA, but not for the muscle layer.
Conclusion The use of an OCA may be helpful for reducing surface heat generation and enhance the light penetration depth in various near-infrared laser treatments.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Rastegar S / 1992 / Theoretical analysis of equivalency of high-power diode laser(810 nm)and Nd : YAG laser(1064 nm)for coagulation of tissue : predictions for prostate coagulation / Proc SPIE 1646:150~160
Alayat MS / 2014 / Long-term effect of high-intensity laser therapy in the treatment of patients with chronic low back pain : a randomized blinded placebo-controlled trial / Lasers Med Sci 29:1065~1073
Lee S / 2014 / Development of the theragnostic optical system for a high-intensity laser therapy(HILT) / Lasers Med Sci 29:1585~1591
Alayat MSM / 2017 / Efficacy of pulsed Nd : YAG laser in the treatment of patients with knee osteoarthritis : a randomized controlled trial / Lasers Med Sci 32:503~511
Taylor DL / 1997 / Comparison of a high power diode laser with the Nd : YAG laser using in situ wound strength analysis of healing cutaneous incisions / Lasers Surg Med 21:248~254
Alayat MS / 2014 / Long-term effect of high-intensity laser therapy in the treatment of patients with chronic low back pain : a randomized blinded placebo-controlled trial / Lasers Med Sci 29:1065~1073
Lee S / 2014 / Development of the theragnostic optical system for a high-intensity laser therapy(HILT) / Lasers Med Sci 29:1585~1591
Alayat MSM / 2017 / Efficacy of pulsed Nd : YAG laser in the treatment of patients with knee osteoarthritis : a randomized controlled trial / Lasers Med Sci 32:503~511
Taylor DL / 1997 / Comparison of a high power diode laser with the Nd : YAG laser using in situ wound strength analysis of healing cutaneous incisions / Lasers Surg Med 21:248~254
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