지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.8
- 수록면
- 256 - 264 (9page)
이용수
초록· 키워드
오류제보하기
Background: Fluid overload prior to continuous renal replacement therapy (CRRT) is an important prognostic factor. Thus, precise evaluation of fluid status is necessary to treat such patients. In this study, we investigated whether fluid assessment using bioelectrical impedance analysis (BIA) can predict outcomes in critically ill patients requiring CRRT.
Methods: A prospective observational study was performed in patients who were admitted to the intensive care unit and who required CRRT. BIA was conducted before CRRT; then, the ratio of extracellular water to total body water (ECW/TBW) was derived to estimate volume status.
Results: A total of 31 patients treated with CRRT were included. There were 18 men (58.1%), and the median age was 67 years (interquartile range, 51 to 78 years). Fourteen patients (45.2%) died within 28 days after CRRT initiation. Patients were divided into 16 with ECW/TBW ≥0.41 and 15 with ECW/TBW <0.41. Survival rate within 28 days was different between the two groups (P = 0.044).
Cox regression analysis revealed a relationship between ECW/TBW ≥0.41 and 28-day mortality, but it was not statistically significant (hazard ratio, 3.0; 95% confidence interval, 0.9 to 9.8; P = 0.061). Lastly, the area under the curve of ECW/TBW for 28-day mortality was analyzed. The area under the curve of ECW/TBW was 0.73 (95% confidence interval, 0.54 to 0.92), and this was significant (P = 0.037).
Conclusions: Fluid status can be assessed using BIA in critically ill patients requiring CRRT, and BIA can predict mortality. Further large trials are needed to confirm the usefulness of BIA in critically ill patients.
목차
등록된 정보가 없습니다.
참고문헌 (35)
참고문헌 신청
Hoste EA / 2008 / Epidemiology of acute kidney injury: how big is the problem? / Crit Care Med 36(4 Suppl):S146~S151
Uchino S / 2005 / Acute renal failure in critically ill patients: a multinational, multicenter study / JAMA 294:813~818
Liu KD / 2006 / Timing of initiation of dialysis in critically ill patients with acute kidney injury / Clin J Am Soc Nephrol 1:915~919
Gaudry S / 2016 / Initiation strategies for renalreplacement therapy in the intensive care unit / N Engl J Med 375:122~133
Bouchard J / 2009 / Fluid accumulation, survival and recovery of kidney function in critically ill patients with acute kidney injury / Kidney Int 76:422~427
Uchino S / 2005 / Acute renal failure in critically ill patients: a multinational, multicenter study / JAMA 294:813~818
Liu KD / 2006 / Timing of initiation of dialysis in critically ill patients with acute kidney injury / Clin J Am Soc Nephrol 1:915~919
Gaudry S / 2016 / Initiation strategies for renalreplacement therapy in the intensive care unit / N Engl J Med 375:122~133
Bouchard J / 2009 / Fluid accumulation, survival and recovery of kidney function in critically ill patients with acute kidney injury / Kidney Int 76:422~427
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