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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.8
- 수록면
- 112 - 122 (11page)
- DOI
- https://doi.org/10.17945/kjbt.2021.32.2.112
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초록· 키워드
오류제보하기
Background: In ABO-incompatible (ABOi) solid organ transplantation, the minimization and management of isoagglutinin (IA) against donor ABO antigens between before and two weeks after transplantation is important for preventing hyper-acute rejection. Several factors that can affect the IA titer have been reported. This is the first study to evaluate whether there are IA titer differences between kidney transplantation (KT) and liver transplantation (LT) recipients.
Methods: Thirty-eight KT and 32 LT type O recipients, who underwent ABOi KT or LT between March 2013 and March 2018, were enrolled consecutively. The IgM IA and IgG IA titers of the LT and KT recipients at different time points (initial, operation day [day-0], postoperative one week, four weeks, and one year) were evaluated.
Results: The LT recipients showed higher initial IgG IA titers than the KT recipients (P=0.01). This higher titer in the LT recipients persisted during the critical phase (from before transplantation to postoperative one week).
The IgG and IgM IA titers were similar in the KT and LT recipients at postoperative four weeks.
Conclusion: The difference in IA titer between the underlying diseases should be considered in the desensitization protocol before ABOi SOT. (Korean J Blood Transfus 2021;32:112-122)
목차
등록된 정보가 없습니다.
참고문헌 (36)
참고문헌 신청
Takahashi K / 2013 / ABO-incompatible kidney transplantation / Transplant Rev(Orlando) 27:1~8
KONOS / 2020 / Annual report of organ transplantation and human tissue donation in 2019 :39~40
Tasaki M / 2017 / Acquired downregulation of donor-specific antibody production after ABOincompatible kidney transplantation / Am J Transplant 17:115~128
Morath C / 2017 / ABO-incompatible kidney transplantation / Front Immunol 8:234
Klein HG / 2014 / Mollison’s blood transfusion in clinical medicine / John Wiley & Sons :129~130
KONOS / 2020 / Annual report of organ transplantation and human tissue donation in 2019 :39~40
Tasaki M / 2017 / Acquired downregulation of donor-specific antibody production after ABOincompatible kidney transplantation / Am J Transplant 17:115~128
Morath C / 2017 / ABO-incompatible kidney transplantation / Front Immunol 8:234
Klein HG / 2014 / Mollison’s blood transfusion in clinical medicine / John Wiley & Sons :129~130
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