지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.5
- 수록면
- 375 - 383 (9page)
이용수
초록· 키워드
오류제보하기
To provide insights into the role of innate immune responses in vaccine-mediated protection, we investigated the effect of Marek’s disease (MD) vaccine, CVI988/Rispens, on the expression patterns of selected genes associated with activation of macrophages in MD-resistant and MD-susceptible chicken lines. Upregulation of interferon , interleukin (IL)-1, IL-8, and IL-12 at different days post-inoculation (dpi) revealed activation of macrophages in both chicken lines. A strong immune response was induced in cecal tonsils of the susceptible line at 5 dpi. The highest transcriptional activities were observed in spleen tissues of the resistant line at 3 dpi. No increase in the population of CD3<sup>+</sup> T cells was observed in duodenum of vaccinated birds at 5 dpi indicating a lack of involvement of the adaptive immune system in the transcriptional profiling of the tested genes. There was, however, an increase in the number of macrophages in the duodenum of vaccinated birds. The CVI988/Rispens antigen was detected in the duodenum and cecal tonsils of the susceptible line at 5 dpi but not in the resistant line. This study sheds light on the role of macrophages in vaccine-mediated protection against MD and on the possible development of new recombinant vaccines with enhanced innate immune system activation properties.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Regulation of Macrophage Activation and Differentiation in Atherosclerosis
지질·동맥경화학회지
2021 .09
-
Differential Activation of Macrophages Based on Their Environment in Advanced Age
전남의대학술지
2020 .01
-
A Missing Subepithelial Tumor in the Duodenum
Korean Journal of Helicobacter Upper Gastrointestinal Research
2020 .01
-
Primary Follicular Lymphoma of the Duodenum: A Case Report
Journal of Pathology and Translational Medicine
2016 .01
-
A Huge Mass of the Duodenum with Upper Gastrointestinal Bleeding
Korean Journal of Helicobacter Upper Gastrointestinal Research
2018 .01
-
Evaluation of stockpiled emergency vaccines for Foot-and-Mouth Disease in Korea, 2019-2021
예방수의학회지
2022 .12
-
Immune responses in pigs and cattle vaccinated with half-volume foot-and-mouth disease vaccine
Journal of Veterinary Science
2017 .08
-
Pro-Inflammatory Role of S1P<sub>3</sub> in Macrophages
Biomolecules & Therapeutics(구 응용약물학회지)
2019 .01
-
Application of ex-vivo generated macrophages as potential cell therapy
한국실험동물학회 학술발표대회 논문집
2022 .07
-
The regulatory function of Hes1 in metabolic disease related macrophage
한국실험동물학회 학술발표대회 논문집
2020 .07
-
Analysis of porcine macrophage immune response to antigenic molecules and short chain fatty acids
Journal of Biomedical and Translational Research
2015 .01
-
Therapeutic Vaccines and Nucleic Acid Drugs for Cardiovascular Disease
지질·동맥경화학회지
2024 .09
-
Correlation between Tonsil Shadow Area on Skull Lateral View and Tonsil Volume after Tonsillectomy
sleep medicine research
2019 .01
-
Review of COVID-19 Vaccines and Their Evidence in Older Adults
Annals of geriatric medicine and research
2021 .01
-
Vaccines in the United States: a systematic review on history of evolution, regulations, licensing, and future challenges
Clinical and Experimental Vaccine Research
2020 .01
-
Immuno-protective effect of commercial IBD vaccines against emerging novel variant infectious bursal disease virus in specific-pathogen-free chickens
Journal of Veterinary Science
2024 .09
-
Should the COVID-19 Vaccine be Administered Simultaneously with Other Vaccines?
Infection and Chemotherapy
2021 .09
-
New Insights Into Tissue Macrophages : From Their Origin to the Development of Memory
Immune Network
2015 .08
-
Melatonin significantly down-regulates long non-coding RNA Cox2 in M1 macrophages stimulated with LPS
한국실험동물학회 학술발표대회 논문집
2022 .07
-
Exploring the experience of developing COVID-19 vaccines in Iran
Clinical and Experimental Vaccine Research
2023 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2023-528-001366817