지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.9
- 수록면
- 130 - 134 (5page)
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초록· 키워드
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Neuropsychiatric events are commonly reported in patients with systemic lupus erythematosus and they are an important contributor to both morbidity and mortality. Neuropsychiatric systemic lupus erythematosus (NPSLE) mainly involves the central nervous system, and rarely invades the peripheral nervous system. A 12-year-old girl presented with sudden-onset motor weakness in her lower extremities and face, as well as drowsiness. Brain magnetic resonance imaging and angiography produced no abnormal findings, and a cerebrospinal fluid examination revealed only pleocytosis. Reticular erythema in the extremities, oral ulcers, and a dry mouth were noted at her first visit, but a malar rash appeared on the third day with positivity for serum antinuclear and anti-dsDNA antibodies. Therefore a high- dose steroid was administered based on a diagnosis of NPSLE. An ophthalmologic examination, salivary gland scan, and biopsy of minor salivary gland resulted in the additional diagnosis of Sjogren’s syndrome. The reported patient represents a rare pediatric case of NPSLE accompanied with Sjogren’s syndrome, presenting as Bickerstaff’s brainstem encephalitis and being successfully treated with early steroid pulse therapy.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Zhou HQ / 2008 / Clinical features and outcome of neuropsychiatric lupus in Chinese : analysis of 240 hospitalized patients / Lupus 17:93~99
Kampylafka EI / 2013 / Incidence and prevalence of major central nervous system involvement in systemic lupus erythematosus: a 3-year prospective study of 370 patients / PLoS One 8:e55843
So-Yeon Kim / 2014 / Concomitant Occurrence of Cervical Myelopathy, Cerebral Infarction, and Peripheral Neuropathy in Systemic Lupus Erythematosus: A Case Report / Annals of Rehabilitation Medicine 38(2):263~268
Bertsias GK / 2010 / Pathogenesis, diagnosis and management of neuropsychiatric SLE manifestations / Nat Rev Rheumatol 6:358~367
Sanna G / 2003 / Central nervous system lupus : a clinical approach to therapy / Lupus 12:935~942
Kampylafka EI / 2013 / Incidence and prevalence of major central nervous system involvement in systemic lupus erythematosus: a 3-year prospective study of 370 patients / PLoS One 8:e55843
So-Yeon Kim / 2014 / Concomitant Occurrence of Cervical Myelopathy, Cerebral Infarction, and Peripheral Neuropathy in Systemic Lupus Erythematosus: A Case Report / Annals of Rehabilitation Medicine 38(2):263~268
Bertsias GK / 2010 / Pathogenesis, diagnosis and management of neuropsychiatric SLE manifestations / Nat Rev Rheumatol 6:358~367
Sanna G / 2003 / Central nervous system lupus : a clinical approach to therapy / Lupus 12:935~942
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