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자료유형
학술저널
저자정보
Dong Hoon Suh (Seoul National University Bundang Hospital) Hyeong In Ha (Department of Obstetrics and Gynecology Pusan National University Yangsan Hospital Korea) Yeon Jee Lee (Research Institute and Hospital National Cancer Center Goyang Korea) Jiwon Lim (National Cancer Control Institute National Cancer Center Goyang Korea) Young-Joo Won (National Cancer Center) Myong Cheol Lim (Research Institute and Hospital National Cancer Center Goyang Korea)
저널정보
대한부인종양학회 Journal of Gynecologic Oncology Journal of Gynecologic Oncology Vol.34 No.2
발행연도
2023.3
수록면
1 - 9 (9page)
DOI
https://doi.org/10.3802/jgo.2023.34.e39

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Objective: To describe the incidence and sur vival outcomes of uterine cer vical cancer during1999–2018. Methods: Patients who were diagnosed with cer vical cancer during 1999–2018 were identifiedin the Korea Central Cancer Registr y. Age-standardized incidence rates (ASRs) and annualpercent changes (APCs) were calculated. Sur vival rates by histology, year of diagnosis(1999–2008 vs. 2009–2018), stage, and age at diagnosis were analyzed. Results: The absolute incidence of cer vical cancer decreased over 20 years from 4,488 in 1999to 3,500 in 2018, with an APC of −3.42% (p<0.0001). While ASR of squamous cell carcinoma(SCCA) more than halved from 13.27 per 100,000 in 1999 to 6.16 in 2018 (APC, −4.04%),adenocarcinoma continued to rise (ASR, 1.30 per 100,000 to 1.92; APC, 1.52%; p<0.0001). Patients with adenocarcinoma were younger than those with SCCA (mean, 49.9±12.7 vs. 52.9±14.6 years; p<0.0001). Five-year sur vival rate of cer vical cancer patients overall was 78.0%. Adenocarcinoma had poorer sur vival than SCCA (5-year sur vival rate, 76.8% vs. 79.8%;p<0.0001). There was no sur vival difference between patients who were diagnosed between1999–2008 and 2009–2018. Earlier-stage disease had better sur vival (5-year sur vival rate forlocalized, regional, and distant disease, 90.0% vs. 69.9% vs. 26.5%; p<0.0001). Younger patientsaged <50 years had better sur vival than those aged ≥50 years (87.1% vs. 69.8%; p<0.0001). Conclusion: The incidence of SCCA of the uterine cer vix declined while adenocarcinomacontinued to increase slowly but significantly from 1999 to 2018 in Korea. Adenocarcinomawas diagnosed at a younger age, but had poorer sur vival outcome than SCCA.

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