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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.3
- 수록면
- 1 - 10 (10page)
- DOI
- https://doi.org/10.3802/jgo.2023.34.e13
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초록· 키워드
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Background: The impact of para-aortic lymphadenectomy (PALD) on prognosis and qualityof life (QoL) for IB2-IIA2 cer vical cancer patients remain controversial. And whetherintraoperative frozen pathology exam on common iliac lymph nodes could help predict para-aortic lymph node (PALN) metastasis was unanswered with high-level evidence.
Methods: A multi-center, randomized controlled study is intended to investigate the effectof PALD on the prognosis and QoL in cer vical cancer patients and to assess the value ofintraoperative frozen pathological evaluation of common iliac nodes metastasis for theprediction of PALN metastasis. After choosing whether to receive intraoperative frozenpathological examination of bilateral common iliac lymph nodes, eligible patients will berandomly assigned (1:1) to receive PALD or not. The primar y end point is 2-year progression-free sur vival (PFS). The secondar y end points include 5-year PFS, 2-year overall sur vival (OS),5-year OS, adverse events (AEs) caused by PALD, AEs caused by radiotherapy and QoL. A totalof 728 patients will be enrolled from 8 hospitals in China within 3-year period and followedup for 5 years.
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