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논문 기본 정보

자료유형
학술저널
저자정보
Kye-Hwan Kim (Gyeongsang National University) Seung Do Lee (Gyeongsang National University) Hyo Jin Lee (Gyeongsang National University) Hangyul Kim (Gyeongsang National University) Hye Ree Kim (Gyeongsang National University) Yun Ho Cho (Gyeongsang National University) Jeong Yoon Jang (Gyeongsang National University Changwon Hospital) Min Gyu Kang (Gyeongsang National University) Jin-Sin Koh (Gyeongsang National University) Seok-Jae Hwang (Gyeongsang National University Hospital) Jin-Yong Hwang (Gyeongsang National University Hospital) Jeong Rang Park (Gyeongsang National University Hospital)
저널정보
한국심초음파학회 Journal of Cardiovascular Imaging Journal of Cardiovascular Imaging 제31권 제2호
발행연도
2023.4
수록면
85 - 95 (11page)

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BACKGROUND: The prognostic utility of follow-up transthoracic echocardiography (FU-TTE) in patients with hypertrophic cardiomyopathy (HCM) is unclear, specifically in terms of whether changes in echocardiographic parameters in routine FU-TTE parameters are associated with cardiovascular outcomes. METHODS: From 2010 to 2017, 162 patients with HCM were retrospectively enrolled in this study. Using echocardiography, HCM was diagnosed based on morphological criteria. Patients with other diseases that cause cardiac hypertrophy were excluded. TTE parameters at baseline and FU were analyzed. FU-TTE was designated as the last recorded value in patients who did not develop any cardiovascular event or the latest exam before event development. Clinical outcomes were acute heart failure, cardiac death, arrhythmia, ischemic stroke, and cardiogenic syncope. RESULTS: Median interval between the baseline TTE and FU-TTE was 3.3 years. Median clinical FU duration was 4.7 years. Septal trans-mitral velocity/mitral annular tissue Doppler velocity (E/e’), tricuspid regurgitation velocity, left ventricular ejection fraction (LVEF), and left atrial volume index (LAVI) at baseline were recorded. LVEF, LAVI, and E/e’ values were associated with poor outcomes. However, no delta values predicted HCM-related cardiovascular outcomes. Logistic regression models incorporating changes in TTE parameters had no significant findings. Baseline LAVI was the best predictor of a poor prognosis. In survival analysis, an already enlarged or increased size LAVI was associated with poorer clinical outcomes. CONCLUSIONS: Changes in echocardiographic parameters extracted from TTE did not assist in predicting clinical outcomes. Cross-sectionally evaluated TTE parameters were superior to changes in TTE parameters between baseline and FU at predicting cardiovascular events.

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