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논문 기본 정보

자료유형
학술저널
저자정보
Baeg Song In (Division of Nephrology Department of Internal Medicine Myongji Hospital Hanyang University Medical Center Goyang Republic of Korea.) Lee Kyungho (Division of Nephrology Department of Medicine Sungkyunkwan University School of Medicine Samsung Medical Center Seoul Republic of Korea.) Jeon Junseok (Division of Nephrology Department of Medicine Sungkyunkwan University School of Medicine Samsung Medical Center Seoul Republic of Korea.) Jang Hye Ryoun (Division of Nephrology Department of Medicine Sungkyunkwan University School of Medicine Samsung Medical Center Seoul Republic of Korea.)
저널정보
전해질고혈압연구회 Electrolytes & Blood Pressure Electrolytes & Blood Pressure Vol.20 No.2
발행연도
2022.12
수록면
64 - 75 (12page)
DOI
10.5049/EBP.2022.20.2.64

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Despite the lack of proven superiority in mortality compared to intermittent hemo dialysis, continuous renal replacement therapy (CRRT) is the preferred renal repla cement therapy modality for critically ill patients with acute kidney injury (AKI) due to better hemodynamic stability and steady correction of electrolytes distur bances and volume overload. Multiple and complex electrolyte disorders in patients with AKI can be managed effectively with CRRT because controlled and predictable correction is feasible. Thus, CRRT has an advantage with safety over conventional hemodialysis, especially in patients with both renal dysfunction and electrolyte disorder that require a sophisticated treatment with avoidance of rapid correction. On the contrary, CRRT can potentially lead to paradoxical disturbance of electrolytes such as hypokalemia or hypophosphatemia, especially in patients under high dose or prolonged duration of CRRT treatment. These electrolytes rela ted complications can be prevented with close monitoring followed by the appro priate use of CRRT fluids. Although there is a lack of solid evidence and standardi zed guideline for CRRT prescriptions, optimal management of various electrolyte disturbances can be achieved with individualized and tailored dialysate and replacement fluid prescriptions. Several commercially available CRRT solutions with varying compositions provide flexibility to manage electrolyte disorders and maintain the stability of electrolyte. In this review, we discuss various prescription methods to manage common electrolyte imbalances as well as preventative stra tegies to maintain electrolyte homeostasis during CRRT providing detailed proto cols used in our center. This review may contribute to future research that can lead to the development of clinical practice guidelines.

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